Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …

Adverse childhood experiences (ACEs), such as maltreatment and severe household
dysfunction, represent a significant threat to public health as ACEs are associated with …

Background Exposure to early-life adversity is known to predict DNA methylation (DNAm)
patterns that may be related to psychiatric risk. However, few studies have investigated …

Methyl donors such as choline, betaine, folic acid, methionine, and vitamins B6 and B12 are
critical players in the one-carbon metabolism and have neuroprotective functions. The one …

The putative effects of early-life stress (ELS) on later behavior and neurobiology have been
widely investigated. Recently, microglia have been implicated in mediating some of the …

Understanding the association between fetal nervous system structure and functioning
should be an important goal in neurodevelopmental sciences, especially when considering …

Irritable bowel syndrome (IBS) is a complex multifactorial condition including alterations of
the gut–brain axis, intestinal permeability, mucosal neuro-immune interactions, and …

Today, it is possible to investigate the biological paths and mechanisms that link mental life
to biological life. Emotions, feelings, desires, and cognitions influence biological systems. In …

Background Many observational studies have found a direct association between adverse in
utero, perinatal and postnatal exposures and offspring's depression. These findings are …

Early life adversity (ELA) is a major risk factor for the development of pathology, including
anxiety disorders. Neurodevelopmental and behavioral outcomes following ELA are …