Unmet clinical needs in elderly patients receiving direct Oral anticoagulants for stroke prevention in non-valvular atrial fibrillation

G Botto, P Ameri, M Cappellari, F Dentali, N Ferri… - Advances in …, 2021 - Springer
Vitamin K antagonists have been used for many years as the treatment of choice for long-
term oral anticoagulation in patients with non-valvular atrial fibrillation. Unfortunately, the …

The influence of atrial high-rate episodes on stroke and cardiovascular death: an update

T Toennis, E Bertaglia, A Brandes, W Dichtl… - Europace, 2023 - academic.oup.com
Atrial high-rate episodes (AHRE) are atrial tachyarrhythmias detected by continuous rhythm
monitoring by pacemakers, defibrillators, or implantable cardiac monitors. Atrial high-rate …

Clinical outcomes in patients with atrial fibrillation treated with DOACs in a specialized anticoagulation center: Critical appraisal of real-world data

C Moret, R Acosta-Isaac, S Mojal, M Corrochano… - Plos one, 2023 - journals.plos.org
Aims Direct oral anticoagulants (DOAC) are progressively replacing vitamin K antagonists in
the prevention of thromboembolism in patients with atrial fibrillation. However, their real …

Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry

GYH Lip, A Kotalczyk, C Teutsch, HC Diener… - Clinical research in …, 2022 - Springer
Background and purpose Prospectively collected data comparing the safety and
effectiveness of individual non-vitamin K antagonists (NOACs) are lacking. Our objective …

Dabigatran versus vitamin K antagonists for atrial fibrillation in clinical practice: final outcomes from Phase III of the GLORIA-AF registry

MV Huisman, C Teutsch, S Lu, HC Diener… - Clinical Research in …, 2022 - Springer
Background Prospectively collected, routine clinical practice-based data on antithrombotic
therapy in non-valvular atrial fibrillation (AF) patients are important for assessing real-world …

Do baseline characteristics and treatments account for geographical disparities in the outcomes of patients with newly diagnosed atrial fibrillation? The prospective …

KAA Fox, S Virdone, JP Bassand, AJ Camm, S Goto… - BMJ open, 2022 - bmjopen.bmj.com
Objective In patients with newly diagnosed atrial fibrillation (AF), do baseline risk factors and
stroke prevention strategies account for the geographically diverse outcomes. Design Global …

Two-year outcomes of UK patients newly diagnosed with atrial fibrillation: findings from the prospective observational cohort study GARFIELD-AF

PN Apenteng, S Virdone, FDR Hobbs, AJ Camm… - British Journal of …, 2022 - bjgp.org
Background The outcomes of patients newly diagnosed with atrial fibrillation (AF) following
the introduction of direct-acting oral anticoagulants are not well known. Aim To determine …

Determinants and clinical outcomes of patients who refused anticoagulation: findings from the global GARFIELD-AF registry

P Apenteng, S Virdone, J Camm, KAA Fox… - Open …, 2023 - openheart.bmj.com
Objective There is a substantial incidence of stroke in patients with atrial fibrillation (AF) not
receiving anticoagulation. The reasons for not receiving anticoagulation are generally …

To treat or not to treat: a comparative effectiveness analysis of oral anticoagulant outcomes among US nursing home residents with atrial fibrillation

Q Chen, J Baek, R Goldberg, J Tjia, K Lapane… - BMC geriatrics, 2024 - Springer
Background Nursing home residents with atrial fibrillation are at high risk for ischemic stroke,
but most are not treated with anticoagulants. This study compared the effectiveness and …

Impact of patient selection in clinical trials: application of ROCKET AF and ARISTOTLE criteria in GARFIELD-AF

JCL Himmelreich, S Virdone, J Camm, K Pieper… - Open …, 2024 - openheart.bmj.com
Background The extent to which differences in results from Apixaban for Reduction in Stroke
and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) and Rivaroxaban Once …