Pesticides at brain borders: Impact on the blood-brain barrier, neuroinflammation, and neurological risk trajectories

N Cresto, I Forner-Piquer, A Baig, M Chatterjee… - Chemosphere, 2023 - Elsevier
Pesticides are omnipresent, and they pose significant environmental and health risks.
Translational studies indicate that acute exposure to high pesticide levels is detrimental, and …

Environmental impact on the epigenetic mechanisms underlying Parkinson's disease pathogenesis: a narrative review

E Angelopoulou, YN Paudel, SG Papageorgiou… - Brain Sciences, 2022 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder with an
unclear etiology and no disease-modifying treatment to date. PD is considered a …

[HTML][HTML] Proximity to residential and workplace pesticides application and the risk of progression of Parkinson's diseases in Central California

S Li, B Ritz, Y Gong, M Cockburn, AD Folle… - Science of The Total …, 2023 - Elsevier
Background Pesticide exposure has consistently been associated with Parkinson's disease
(PD) onset. Yet, fewer epidemiologic studies have examined whether pesticides influence …

[HTML][HTML] Metal elements and pesticides as risk factors for Parkinson's disease-A review

I Ullah, L Zhao, Y Hai, M Fahim, D Alwayli, X Wang… - Toxicology reports, 2021 - Elsevier
Essential metals including iron (Fe) and manganese (Mn) with known physiological
functions in human body play an important role in cell homeostasis. Excessive exposure to …

Neurobehavioral, neuromotor, and neurocognitive effects in agricultural workers and their children exposed to pyrethroid pesticides: a review

B Lucero, MT Muñoz-Quezada - Frontiers in Human Neuroscience, 2021 - frontiersin.org
In recent years, pyrethroids have emerged as a less toxic alternative to eliminate insect
pests. However, some animal studies and studies with children show that these pesticides …

Detection of pesticides in food products using paper-based devices by UV-induced fluorescence spectroscopy combined with molecularly imprinted polymers

M Vodova, L Nejdl, K Pavelicova, K Zemankova… - Food Chemistry, 2022 - Elsevier
In this proof-of-concept study, we explore the detection of pesticides in food using a
combined power of sensitive UV-induced fingerprint spectroscopy with selective capture by …

Targeting epigenetics as a promising therapeutic strategy for treatment of neurodegenerative diseases

L Zhang, Y Liu, Y Lu, G Wang - Biochemical pharmacology, 2022 - Elsevier
Nowadays, epigenetics is of great research value as a new gateway that can solve the
sophisticated mysteries behind neurodegenerative diseases. Epigenetic mechanisms …

Effect of perinatal exposure to glyphosate and its mixture with 2, 4-D and dicamba on rat dam kidney and thyroid function and offspring's health

AO Docea, AE Cirstea, L Cercelaru, AI Drocas… - Environmental …, 2023 - Elsevier
The increasing use of the herbicide mixture of glyphosate, dicamba and 2-4-D to deal with
glyphosate-resistant weeds raises concerns regarding human health and environmental …

Impact of environmental risk factors on mitochondrial dysfunction, neuroinflammation, protein misfolding, and oxidative stress in the etiopathogenesis of parkinson's …

M Huang, A Bargues-Carot, Z Riaz, H Wickham… - International journal of …, 2022 - mdpi.com
As a prevalent progressive neurodegenerative disorder, Parkinson's disease (PD) is
characterized by the neuropathological hallmark of the loss of nigrostriatal dopaminergic …

ADORA2A rs5760423 and CYP1A2 rs762551 Polymorphisms as Risk Factors for Parkinson's Disease

V Siokas, AM Aloizou, Z Tsouris, I Liampas… - Journal of Clinical …, 2021 - mdpi.com
Background: Parkinson's disease (PD) is the second commonest neurodegenerative
disease. The genetic basis of PD is indisputable. Both ADORA2A rs5760423 and CYP1A2 …