Living organisms are continuously exposed to a myriad of DNA damaging agents that can
impact health and modulate disease‐states. However, robust DNA repair and damage …

An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing
sugars in honey and various processed foods in acidic environments when they are heated …

DNA double-stranded breaks (DSB) are among the most dangerous forms of DNA damage.
Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas mis …

Double-strand DNA breaks are common events in eukaryotic cells, and there are two major
pathways for repairing them: homologous recombination (HR) and nonhomologous DNA …

Isothermal amplification assays, such as loop-mediated isothermal amplification (LAMP),
show great utility for the development of rapid diagnostics for infectious diseases because …

Nearly every DNA polymerase characterized to date exclusively catalyzes the incorporation
of mononucleotides into a growing primer using a DNA or RNA template as a guide to direct …

With the explosion of digital world, the dramatically increasing data volume is expected to
reach 175 ZB (1 ZB= 1012 GB) in 2025. Storing such huge global data would consume tons …

Over the past decades, remarkable progress on phosphoramidite chemistry-based large-
scale de novo oligonucleotide synthesis has been achieved, enabling numerous novel and …

XRCC4 and DNA ligase IV form a complex that is essential for the repair of all double‐strand
DNA breaks by the nonhomologous DNA end joining pathway in eukaryotes. We find here …

Faithful transmission of genetic material is crucial for all organisms since changes in genetic
information may result in genomic instability that causes developmental disorders and …