Biofilm formation is a major concern in various sectors and cause severe problems to public
health, medicine, and industry. Bacterial biofilm formation is a major persistent threat, as it …

Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Tuberculosis is a chronic disease that displays several features commonly associated with
biofilm-associated infections: immune system evasion, antibiotic treatment failures, and …

Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …

The ability to construct and maintain a structured multicellular bacterial community depends
critically on the production of extracellular matrix components (1, 2). While the biofilm matrix …

The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer
membrane that plays a key role in host–pathogen interactions with the innate immune …

Standard follow-up and symptomatic treatment have allowed most patients with cystic
fibrosis to live to young adulthood. However, many patients still die prematurely from …