Plant pan-genomes are the new reference
Recent years have seen a surge in plant genome sequencing projects and the comparison
of multiple related individuals. The high degree of genomic variation observed led to the …
of multiple related individuals. The high degree of genomic variation observed led to the …
Pan-genomics in the human genome era
RM Sherman, SL Salzberg - Nature Reviews Genetics, 2020 - nature.com
Since the early days of the genome era, the scientific community has relied on a single
'reference'genome for each species, which is used as the basis for a wide range of genetic …
'reference'genome for each species, which is used as the basis for a wide range of genetic …
[HTML][HTML] Eight high-quality genomes reveal pan-genome architecture and ecotype differentiation of Brassica napus
JM Song, Z Guan, J Hu, C Guo, Z Yang, S Wang, D Liu… - Nature plants, 2020 - nature.com
Rapeseed (Brassica napus) is the second most important oilseed crop in the world but the
genetic diversity underlying its massive phenotypic variations remains largely unexplored …
genetic diversity underlying its massive phenotypic variations remains largely unexplored …
[HTML][HTML] Pan-genome analysis highlights the extent of genomic variation in cultivated and wild rice
Q Zhao, Q Feng, H Lu, Y Li, A Wang, Q Tian, Q Zhan… - Nature …, 2018 - nature.com
The rich genetic diversity in Oryza sativa and Oryza rufipogon serves as the main sources in
rice breeding. Large-scale resequencing has been undertaken to discover allelic variants in …
rice breeding. Large-scale resequencing has been undertaken to discover allelic variants in …
Phased diploid genome assembly with single-molecule real-time sequencing
While genome assembly projects have been successful in many haploid and inbred
species, the assembly of noninbred or rearranged heterozygous genomes remains a major …
species, the assembly of noninbred or rearranged heterozygous genomes remains a major …
[HTML][HTML] Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding
Crop populations derived from experimental crosses enable the genetic dissection of
complex traits and support modern plant breeding. Among these, multi-parent populations …
complex traits and support modern plant breeding. Among these, multi-parent populations …
[HTML][HTML] Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement
Upland cotton is a model for polyploid crop domestication and transgenic improvement.
Here we sequenced the allotetraploid Gossypium hirsutum L. acc. TM-1 genome by …
Here we sequenced the allotetraploid Gossypium hirsutum L. acc. TM-1 genome by …
[HTML][HTML] 1,135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana
Arabidopsis thaliana serves as a model organism for the study of fundamental physiological,
cellular, and molecular processes. It has also greatly advanced our understanding of …
cellular, and molecular processes. It has also greatly advanced our understanding of …
[HTML][HTML] Super-pangenome by integrating the wild side of a species for accelerated crop improvement
The pangenome provides genomic variations in the cultivated gene pool for a given species.
However, as the crop's gene pool comprises many species, especially wild relatives with …
However, as the crop's gene pool comprises many species, especially wild relatives with …
[HTML][HTML] Determination and inference of eukaryotic transcription factor sequence specificity
Transcription factor (TF) DNA sequence preferences direct their regulatory activity, but are
currently known for only∼ 1% of eukaryotic TFs. Broadly sampling DNA-binding domain …
currently known for only∼ 1% of eukaryotic TFs. Broadly sampling DNA-binding domain …