Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

Diagnostic and prognostic biomarkers in cholangiocarcinoma

RIR Macias, M Kornek, PM Rodrigues… - Liver …, 2019 - Wiley Online Library
The high mortality rate of cholangiocarcinoma (CCA) is due, in part, to the lack of non‐
invasive approaches able to accurately detect this silent tumour at early stages, when …

[HTML][HTML] MiR-21 promotes intrahepatic cholangiocarcinoma proliferation and growth in vitro and in vivo by targeting PTPN14 and PTEN

LJ Wang, CC He, X Sui, MJ Cai, CY Zhou, JL Ma… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Intrahepatic cholangiocarcinoma (ICC) constitutes the second-most common primary
hepatic malignancy. MicroRNAs (miRNAs) play important roles in the pathogenesis of ICC …

[HTML][HTML] The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma

RIR Macias, JM Banales, B Sangro, J Muntané… - … et Biophysica Acta (BBA …, 2018 - Elsevier
The poor prognosis of cholangiocarcinoma (CCA) is in part due to late diagnosis, which is
currently achieved by a combination of clinical, radiological and histological approaches …

Intrahepatic cholangiocarcinoma: Molecular markers for diagnosis and prognosis

AA Rahnemai-Azar, A Weisbrod, M Dillhoff, C Schmidt… - Surgical oncology, 2017 - Elsevier
Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver tumor
with increasing incidence worldwide. The outcome of patients with iCCA is dismal owing to …

[HTML][HTML] Liquid biopsy in cholangiocarcinoma: Current status and future perspectives

G Rompianesi, M Di Martino… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) are a heterogeneous group of tumors in terms of aetiology,
natural history, morphological subtypes, molecular alterations and management, but all …

Prognostic and predictive molecular markers in cholangiocarcinoma

S Pavicevic, S Reichelt, D Uluk, I Lurje, C Engelmann… - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma (CCA) is a heterogenous and aggressive
malignancy of the intra-and extrahepatic biliary tract, marked by a steeply rising incidence …

MicroRNAs in parasitic helminthiases: current status and future perspectives

P Cai, GN Gobert, DP McManus - Trends in parasitology, 2016 - cell.com
MicroRNAs (miRNAs) play a variety of roles in diverse biological processes at the post-
transcriptional regulatory level. Although numerous miRNAs have been identified in …

Biliary tract cancers: treatment updates and future directions in the era of precision medicine and immuno-oncology

A Manne, E Woods, A Tsung, A Mittra - Frontiers in Oncology, 2021 - frontiersin.org
The effective management of biliary tract cancers (BTCs) has been hampered by limited
options for systemic therapy. In recent years, the focus on precision medicine has made …

Parasite-derived microRNAs in plasma as novel promising biomarkers for the early detection of hydatid cyst infection and post-surgery follow-up

Z Alizadeh, M Mahami-Oskouei, A Spotin, T Kazemi… - Acta tropica, 2020 - Elsevier
Currently, cystic echinococcosis (CE) follow-up is a serious concern among surgeons.
MicroRNAs (miRNAs) are small, endogenous, non-coding RNAs which are present in …