Cancer therapy with accelerated charged particles is one of the most valuable biomedical
applications of nuclear physics. The technology has vastly evolved in the past 50 years, the …

Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …

Nanoparticle-based radioenhancement is a promising strategy for extending the therapeutic
ratio of radiotherapy. While (pre) clinical results are encouraging, sound mechanistic …

Background Clinical data suggest that the relative biological effectiveness (RBE) in proton
therapy (PT) varies with linear energy transfer (LET). However, LET calculations are neither …

Objective. To propose a mathematical model for applying ionization detail (ID), the detailed
spatial distribution of ionization along a particle track, to proton and ion beam radiotherapy …

The chemical stage of the Monte Carlo track-structure simulation code Geant4-DNA has
been revised and validated. The root-mean-square (RMS) empirical parameter that dictates …

Objective. In pencil beam scanning particle therapy, a short treatment delivery time is
paramount for the efficient treatment of moving targets with motion mitigation techniques …

The use and interest in Monte Carlo (MC) techniques in the field of medical physics have
been rapidly increasing in the past years. This is the case especially in particle therapy …

Naturally occurring background radiation is a potential source of correlated decoherence
events in superconducting qubits that will challenge error-correction schemes. In order to …

Dose calculation algorithms based on Monte Carlo (MC) simulations play a crucial role in
radiotherapy. Here, the development and benchmarking of a novel MC dose engine …