High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …

Aquaporins constitute a family of transmembrane proteins that function to transport water
and other small solutes across the cell membrane. Aquaporins family members are found in …

Aquaporins are integral membrane proteins which are also known as water channel
proteins. They aid quick transportation of water across membranes and are important in …

Congenital cataracts are associated with gene mutations, yet the underlying mechanism
remains largely unknown. Here we reported an embryonic chick lens model that closely …

The etiology of age-related cortical cataracts is not well understood but is speculated to be
related to alterations in cell adhesion and/or the changing mechanical stresses occurring in …

Purpose: We reported previously that aquaporin 0 (AQP0) modulates lens fiber cell gap
junction (GJ) channel function. The present study was conducted to find out whether the C …

Lens-specific beaded filament (BF) proteins CP49 and filensin interact with the C-terminus of
the water channel protein Aquaporin 0 (AQP0). Previously we have reported that a C …

Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, 13 AQPs, distributed widely in …

Purpose Glutathione peroxidase 1 (GPX1) and catalase are expressed in the lens epithelial
cells and cortical fiber cells, where they detoxify H2O2 to reduce oxidative stress, which is a …

The purpose of this investigation was to find out whether C-terminally end-cleaved
aquaporin 0 (AQP0), that is present predominantly in the lens mature fiber cells of the WT …