Assessment of precision and accuracy of brain white matter microstructure using combined diffusion MRI and relaxometry

S Coelho, Y Liao, F Szczepankiewicz… - Human Brain …, 2024 - Wiley Online Library
Joint modeling of diffusion and relaxation has seen growing interest due to its potential to
provide complementary information about tissue microstructure. For brain white matter (WM) …

Volume electron microscopy in injured rat brain validates white matter microstructure metrics from diffusion MRI

R Coronado-Leija, A Abdollahzadeh, HH Lee… - Imaging …, 2024 - direct.mit.edu
Biophysical modeling of diffusion MRI (dMRI) offers the exciting potential of bridging the gap
between the macroscopic MRI resolution and microscopic cellular features, effectively …

[HTML][HTML] Improving the assessment of axonal injury in early multiple sclerosis

AA Toubasi, G Cutter, C Gheen, T Vinarsky, K Yoon… - Academic …, 2024 - Elsevier
Rationale and Objectives Several quantitative magnetic resonance imaging (MRI) methods
are available to measure tissue injury in multiple sclerosis (MS), but their pathological …

Optimization and validation of the DESIGNER preprocessing pipeline for clinical diffusion MRI in white matter aging

J Chen, B Ades-Aron, HH Lee, S Mehrin… - Imaging …, 2024 - direct.mit.edu
Various diffusion MRI (dMRI) preprocessing pipelines are currently available to yield more
accurate diffusion parameters. Here, we evaluated accuracy and robustness of the …

Predicting Mesoscopic Larmor Frequency Shifts in White Matter with Diffusion MRI--An In-Silico Monte-Carlo Study

AD Sandgaard, SN Jespersen - arXiv preprint arXiv:2407.06694, 2024 - arxiv.org
This study aims to validate if MRI can measure anisotropic mesoscopic Larmor frequency
shifts from white matter axonal microstructure relative to the B0 direction and if dMRI can …

Lifespan Normative Modeling of Brain Microstructure

JEV Reina, AH Zhu, S Benavidez, CE Moreau, Y Feng… - bioRxiv, 2024 - biorxiv.org
Normative models of brain metrics based on large populations could be extremely valuable
for detecting brain abnormalities in patients with a variety of disorders, including …

Human gray matter microstructure mapped using Neurite Exchange Imaging (NEXI) on a clinical scanner

Q Uhl, T Pavan, T Feiweier, GF Piredda, I Jelescu - bioRxiv, 2024 - biorxiv.org
Biophysical models of diffusion in gray matter (GM) can provide unique information about
microstructure of the human brain, in health and disease. Therefore, their compatibility with …

Mapping Tissue Microstructure in Human White Matter With Diffusion MRI

Y Liao - 2024 - search.proquest.com
Diffusion MRI is uniquely sensitive to in vivo cellular features of tissue microstructure in the
brain white matter. By directly parameterizing the biophysical properties, multi-compartment …