Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Technologies and standardization in research on extracellular vesicles

S Gandham, X Su, J Wood, AL Nocera, SC Alli… - Trends in …, 2020 - cell.com
Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …

C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …

Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

A Sahu, ZJ Clemens, SN Shinde, S Sivakumar, A Pius… - Nature aging, 2021 - nature.com
Heterochronic blood exchange (HBE) has demonstrated that circulating factors restore
youthful features to aged tissues. However, the systemic mediators of those rejuvenating …

COVID-19 salivary Raman fingerprint: innovative approach for the detection of current and past SARS-CoV-2 infections

C Carlomagno, D Bertazioli, A Gualerzi, S Picciolini… - Scientific reports, 2021 - nature.com
The pandemic of COVID-19 is continuously spreading, becoming a worldwide emergency.
Early and fast identification of subjects with a current or past infection must be achieved to …

Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy

Y Liang, BM Lehrich, S Zheng… - Journal of Extracellular …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are released by many cell types and distributed within various
biofluids. EVs have a lipid membrane‐confined structure that allows for carrying unique …

Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure

M Lombardi, R Parolisi, F Scaroni, E Bonfanti… - Acta …, 2019 - Springer
Microglia are highly plastic immune cells which exist in a continuum of activation states. By
shaping the function of oligodendrocyte precursor cells (OPCs), the brain cells which …

Development of extracellular vesicle-based medicinal products: A position paper of the group “Extracellular Vesicle translatiOn to clinicaL perspectiVEs–EVOLVE …

AKA Silva, M Morille, M Piffoux, S Arumugam… - Advanced Drug Delivery …, 2021 - Elsevier
Extracellular vesicles (EV) are emergent therapeutic effectors that have reached clinical trial
investigation. To translate EV-based therapeutic to clinic, the challenge is to demonstrate …