The dopamine D3 receptor, a quarter century later
P Sokoloff, B Le Foll - European Journal of Neuroscience, 2017 - Wiley Online Library
This review updates the existing knowledge suggesting a role for the D3 receptor in
schizophrenia and drug addiction. The D3 receptor is expressed in brain regions controlling …
schizophrenia and drug addiction. The D3 receptor is expressed in brain regions controlling …
[HTML][HTML] Dopamine: an immune transmitter
The dopaminergic system controls several vital central nervous system functions, including
the control of movement, reward behaviors and cognition. Alterations of dopaminergic …
the control of movement, reward behaviors and cognition. Alterations of dopaminergic …
Corticostriatal BDNF and alcohol addiction
Growth factors, long studied for their involvement in neuronal development and plasticity,
also regulate responses to drugs of abuse, including alcohol. This review details the intricate …
also regulate responses to drugs of abuse, including alcohol. This review details the intricate …
Current drug treatments targeting dopamine D3 receptor
Dopamine receptors (DR) have been extensively studied, but only in recent years they
became object of investigation to elucidate the specific role of different subtypes (D1R, D2R …
became object of investigation to elucidate the specific role of different subtypes (D1R, D2R …
[HTML][HTML] Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p is associated with modulation of BDNF and FKBP5 in brain areas of PTSD-related susceptible …
OM Maurel, SA Torrisi, C Barbagallo… - International journal of …, 2021 - mdpi.com
Post-traumatic stress disorder (PTSD) is a neuropsychiatric disorder occurring in susceptible
individuals following a traumatic event. Understanding the mechanisms subserving trauma …
individuals following a traumatic event. Understanding the mechanisms subserving trauma …
Hypodopaminergia and “Precision Behavioral Management”(PBM): it is a generational family affair
L Fried, EJ Modestino, D Siwicki, L Lott… - Current …, 2020 - ingentaconnect.com
Background/Aims: This case series presents the novel Genetic Addiction Risk Score
(GARS®) coupled with a customized pro-dopamine regulator matched to polymorphic …
(GARS®) coupled with a customized pro-dopamine regulator matched to polymorphic …
Polypharmacology of dopamine receptor ligands
S Butini, K Nikolic, S Kassel, H Brückmann… - Progress in …, 2016 - Elsevier
Most neurological diseases have a multifactorial nature and the number of molecular
mechanisms discovered as underpinning these diseases is continuously evolving. The old …
mechanisms discovered as underpinning these diseases is continuously evolving. The old …
Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking
Many abused drugs lead to changes in endogenous brain-derived neurotrophic factor
(BDNF) expression in neural circuits responsible for addictive behaviors. BDNF is a known …
(BDNF) expression in neural circuits responsible for addictive behaviors. BDNF is a known …
[HTML][HTML] Identification of the risk genes associated with vulnerability to addiction: Major findings from transgenic animals
Understanding risk factors for substance use disorders (SUD) can facilitate medication
development for SUD treatment. While a rich literature exists discussing environmental …
development for SUD treatment. While a rich literature exists discussing environmental …
Genes and alcohol consumption: studies with mutant mice
J Mayfield, MA Arends, RA Harris… - International review of …, 2016 - Elsevier
In this chapter, we review the effects of global null mutant and overexpressing transgenic
mouse lines on voluntary self-administration of alcohol. We examine approximately 200 …
mouse lines on voluntary self-administration of alcohol. We examine approximately 200 …