Pharmacogenetics: implications of race and ethnicity on defining genetic profiles for personalized medicine
VE Ortega, DA Meyers - Journal of allergy and clinical immunology, 2014 - Elsevier
Pharmacogenetics is being used to develop personalized therapies specific to subjects from
different ethnic or racial groups. To date, pharmacogenetic studies have been primarily …
different ethnic or racial groups. To date, pharmacogenetic studies have been primarily …
Asthma in Hispanics. An 8-year update
FJ Rosser, E Forno, PJ Cooper… - American journal of …, 2014 - atsjournals.org
This review provides an update on asthma in Hispanics, a diverse group tracing their
ancestry to countries previously under Spanish rule. A marked variability in the prevalence …
ancestry to countries previously under Spanish rule. A marked variability in the prevalence …
Genome-wide patterns of population structure and admixture among Hispanic/Latino populations
K Bryc, C Velez, T Karafet… - Proceedings of the …, 2010 - National Acad Sciences
Hispanic/Latino populations possess a complex genetic structure that reflects recent
admixture among and potentially ancient substructure within Native American, European …
admixture among and potentially ancient substructure within Native American, European …
Assessing individual interethnic admixture and population substructure using a 48–insertion‐deletion (INSEL) ancestry‐informative marker (AIM) panel
NPC Santos, EM Ribeiro‐Rodrigues… - Human …, 2010 - Wiley Online Library
Estimating the proportions of different ancestries in admixed populations is very important in
population genetics studies, and it is particularly important for detecting population …
population genetics studies, and it is particularly important for detecting population …
The Biologistical Construction of Race: Admixture'Technology and the New Genetic Medicine
D Fullwiley - Social studies of science, 2008 - journals.sagepub.com
This paper presents an ethnographic case study of the use of race in two interconnected
laboratories of medical genetics. Specifically, it examines how researchers committed to …
laboratories of medical genetics. Specifically, it examines how researchers committed to …
Genetic ancestry influences asthma susceptibility and lung function among Latinos
Background Childhood asthma prevalence and morbidity varies among Latinos in the
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico
Contemporary genetic variation among Latin Americans human groups reflects population
migrations shaped by complex historical, social and economic factors. Consequently …
migrations shaped by complex historical, social and economic factors. Consequently …
Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa
R Yaeger, A Avila-Bront, K Abdul, PC Nolan… - … Biomarkers & Prevention, 2008 - AACR
Genetic association studies can be used to identify factors that may contribute to disparities
in disease evident across different racial and ethnic populations. However, such studies may …
in disease evident across different racial and ethnic populations. However, such studies may …
Disparities in mortality of hispanic patients with cystic fibrosis in the United States. A national and regional cohort study
J Rho, C Ahn, A Gao, GS Sawicki, A Keller… - American journal of …, 2018 - atsjournals.org
Rationale: Patients of Hispanic origin with cystic fibrosis (CF) are the largest growing
minority, representing 8.5% of patients with CF in the United States. No national survival …
minority, representing 8.5% of patients with CF in the United States. No national survival …
Softwares and methods for estimating genetic ancestry in human populations
The estimation of genetic ancestry in human populations has important applications in
medical genetic studies. Genetic ancestry is used to control for population stratification in …
medical genetic studies. Genetic ancestry is used to control for population stratification in …