Exploring Tumor–Immune Interactions in Co-Culture Models of T Cells and Tumor Organoids Derived from Patients
SR Jeong, M Kang - International Journal of Molecular Sciences, 2023 - mdpi.com
The use of patient-derived tumor tissues and cells has led to significant advances in
personalized cancer therapy and precision medicine. The advent of genomic sequencing …
personalized cancer therapy and precision medicine. The advent of genomic sequencing …
Optimization and fabrication of silver nanoparticles to assess the beneficial biological effects besides the inhibition of pathogenic microbes and their biofilms
HJ Nelagadarnahalli, GK Jacob, D Prakash… - Inorganic Chemistry …, 2023 - Elsevier
We hereby report an approach using tannic acid (TA) as a reductant and stabilizer for the
production of tannic acid-conjugated silver nanoparticles (TA-AgNPs). The synthesis was …
production of tannic acid-conjugated silver nanoparticles (TA-AgNPs). The synthesis was …
A systematic review of patient-derived tumor organoids generation from malignant effusions
S Seghers, M Le Compte, JMH Hendriks… - Critical Reviews in …, 2024 - Elsevier
This review assesses the possibility of utilizing malignant effusions (MEs) for generating
patient-derived tumor organoids (PDTOs). Obtained through minimally invasive procedures …
patient-derived tumor organoids (PDTOs). Obtained through minimally invasive procedures …
Breast cancer associated CD169+ macrophages possess broad immunosuppressive functions but enhance antibody secretion by activated B cells
FB Gunnarsdottir, O Briem, AY Lindgren… - Frontiers in …, 2023 - frontiersin.org
CD169+ resident macrophages in lymph nodes of breast cancer patients are for unknown
reasons associated with a beneficial prognosis. This contrasts CD169+ macrophages …
reasons associated with a beneficial prognosis. This contrasts CD169+ macrophages …
Flow Cytometric Analysis of Macrophages and Cytokines Profile in the Bronchoalveolar Lavage Fluid in Patients with Lung Cancer
I Kwiecień, E Rutkowska, A Raniszewska… - Cancers, 2023 - mdpi.com
Simple Summary Macrophages are an integral part of the tumor microenvironment, playing
a role in immunoregulation. We investigated the antigenic and cytokine macrophages profile …
a role in immunoregulation. We investigated the antigenic and cytokine macrophages profile …
Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids
SA Leon-Icaza, S Bagayoko, R Vergé… - PLoS …, 2023 - journals.plos.org
Mycobacterium abscessus (Mabs) drives life-shortening mortality in cystic fibrosis (CF)
patients, primarily because of its resistance to chemotherapeutic agents. To date, our …
patients, primarily because of its resistance to chemotherapeutic agents. To date, our …
CD47-mediated immune evasion in early-stage lung cancer progression
CH Chuang, YY Zhen, JY Ma, TH Lee, HY Hung… - Biochemical and …, 2024 - Elsevier
Alveolar and interstitial macrophages play crucial roles in eradicating pathogens and
transformed cells in the lungs. The immune checkpoint CD47, found on normal and …
transformed cells in the lungs. The immune checkpoint CD47, found on normal and …
Soluble PD-L1 shows no association to relapse and overall survival in early stage non-small cell lung cancer (NSCLC)
FO Mildner, MM Sykora, H Hackl, A Amann, B Zelger… - Lung Cancer, 2024 - Elsevier
Background Cancer immune evasion is critical in non-small cell lung cancer (NSCLC) and
has been targeted by immunotherapy. High soluble (s) PD-L1 is associated with reduced …
has been targeted by immunotherapy. High soluble (s) PD-L1 is associated with reduced …
[HTML][HTML] The Use of Patient-Derived Organoids in the Study of Molecular Metabolic Adaptation in Breast Cancer
N Glibetic, S Bowman, T Skaggs… - International Journal of …, 2024 - mdpi.com
Around 13% of women will likely develop breast cancer during their lifetime. Advances in
cancer metabolism research have identified a range of metabolic reprogramming events …
cancer metabolism research have identified a range of metabolic reprogramming events …
3D cell culture models in research: applications to lung cancer pharmacology
N Vella, AG Fenech, V Petroni Magri - Frontiers in Pharmacology, 2024 - frontiersin.org
Lung cancer remains one of the leading causes of cancer-related mortality worldwide,
necessitating innovative research methodologies to improve treatment outcomes and …
necessitating innovative research methodologies to improve treatment outcomes and …