DoriC 5.0: an updated database of oriC regions in both bacterial and archaeal genomes

F Gao, H Luo, CT Zhang - Nucleic acids research, 2012 - academic.oup.com
Replication of chromosomes is one of the central events in the cell cycle. Chromosome
replication begins at specific sites, called origins of replication (oriCs), for all three domains …

Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance

Z Zhang, J Li, P Cui, F Ding, A Li, JP Townsend, J Yu - BMC bioinformatics, 2012 - Springer
Background Genetic mutation, selective pressure for translational efficiency and accuracy,
level of gene expression, and protein function through natural selection are all believed to …

Extreme Features of the Galdieria sulphuraria Organellar Genomes: A Consequence of Polyextremophily?

K Jain, K Krause, F Grewe, GF Nelson… - Genome biology and …, 2015 - academic.oup.com
Nuclear genome sequencing from extremophilic eukaryotes has revealed clues about the
mechanisms of adaptation to extreme environments, but the functional consequences of …

Recent advances in the identification of replication origins based on the Z-curve method

F Gao - Current Genomics, 2014 - ingentaconnect.com
Precise DNA replication is critical for the maintenance of genetic integrity in all organisms. In
all three domains of life, DNA replication starts at a specialized locus, termed as the …

The percentage of bacterial genes on leading versus lagging strands is influenced by multiple balancing forces

X Mao, H Zhang, Y Yin, Y Xu - Nucleic acids research, 2012 - academic.oup.com
The majority of bacterial genes are located on the leading strand, and the percentage of
such genes has a large variation across different bacteria. Although some explanations …

Quantitative analysis of correlation between AT and GC biases among bacterial genomes

G Zhang, F Gao - PLoS One, 2017 - journals.plos.org
Due to different replication mechanisms between the leading and lagging strands,
nucleotide composition asymmetries widely exist in bacterial genomes. A general …

The influence of the selection at the amino acid level on synonymous codon usage from the viewpoint of alternative genetic codes

K Pawlak, P Błażej, D Mackiewicz… - International Journal of …, 2023 - mdpi.com
Synonymous codon usage can be influenced by mutations and/or selection, eg, for speed of
protein translation and correct folding. However, this codon bias can also be affected by a …

Association of purine asymmetry, strand-biased gene distribution and PolC within Firmicutes and beyond: a new appraisal

SK Saha, A Goswami, C Dutta - BMC genomics, 2014 - Springer
Abstract Background The Firmicutes often possess three conspicuous genome features:
marked Purine Asymmetry (PAS) across two strands of replication, Strand-biased Gene …

De Novo Assembly and Cluster Analysis of Siberian Larch Transcriptome and Genome

M Sadovsky, Y Putintseva, V Birukov… - … , IWBBIO 2016, Granada …, 2016 - Springer
Abstract We studied Siberian Larch (Larix Sibirica) transcriptome making de novo assembly
and cluster analysis of contigs frequency dictionaries. Also, some preliminary results of …

Strand-biased gene distribution in bacteria is related to both horizontal gene transfer and strand-biased nucleotide composition

H Wu, H Qu, N Wan, Z Zhang, S Hu… - Genomics, Proteomics …, 2012 - academic.oup.com
Although strand-biased gene distribution (SGD) was described some two decades ago, the
underlying molecular mechanisms and their relationship remain elusive. Its facets include …