To build a synapse: signaling pathways in neuromuscular junction assembly
Synapses, as fundamental units of the neural circuitry, enable complex behaviors. The
neuromuscular junction (NMJ) is a synapse type that forms between motoneurons and …
neuromuscular junction (NMJ) is a synapse type that forms between motoneurons and …
Many paths to synaptic specificity
JR Sanes, M Yamagata - Annual Review of Cell and …, 2009 - annualreviews.org
The most impressive structural feature of the nervous system is the specificity of its synaptic
connections. Even after axons have navigated long distances to reach target areas, they …
connections. Even after axons have navigated long distances to reach target areas, they …
LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction
SD Weatherbee, KV Anderson, LA Niswander - 2006 - journals.biologists.com
Low-density lipoprotein receptor-related protein 4 (Lrp4) is a member of a family of
structurally related, single-pass transmembrane proteins that carry out a variety of functions …
structurally related, single-pass transmembrane proteins that carry out a variety of functions …
Synaptic input and Ca2+ activity in zebrafish oligodendrocyte precursor cells contribute to myelin sheath formation
J Li, TG Miramontes, T Czopka, KR Monk - Nature Neuroscience, 2024 - nature.com
In the nervous system, only one type of neuron–glial synapse is known to exist: that between
neurons and oligodendrocyte precursor cells (OPCs), yet their composition, assembly …
neurons and oligodendrocyte precursor cells (OPCs), yet their composition, assembly …
Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost
TT Kummer, T Misgeld, JR Sanes - Current opinion in neurobiology, 2006 - Elsevier
Studies of the vertebrate skeletal neuromuscular junction led to an influential model of how
neurotransmitter receptors accumulate in the postsynaptic membrane. In this model, motor …
neurotransmitter receptors accumulate in the postsynaptic membrane. In this model, motor …
Synaptic vulnerability in neurodegenerative disease
TM Wishart, SH Parson… - … of Neuropathology & …, 2006 - academic.oup.com
Recent developments in our understanding of the pathophysiological mechanisms
underlying degeneration in both the central and peripheral nervous systems have …
underlying degeneration in both the central and peripheral nervous systems have …
Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor
L Jing, JL Lefebvre, LR Gordon, M Granato - Neuron, 2009 - cell.com
Early during neuromuscular development, acetylcholine receptors (AChRs) accumulate at
the center of muscle fibers, precisely where motor growth cones navigate and synapses …
the center of muscle fibers, precisely where motor growth cones navigate and synapses …
Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction
N Singhal, PT Martin - Developmental neurobiology, 2011 - Wiley Online Library
The vertebrate neuromuscular junction (NMJ) remains the best‐studied model for
understanding the mechanisms involved in synaptogenesis, due to its relatively large size …
understanding the mechanisms involved in synaptogenesis, due to its relatively large size …
CDG therapies: from bench to bedside
Congenital disorders of glycosylation (CDG) are a group of genetic disorders that affect
protein and lipid glycosylation and glycosylphosphatidylinositol synthesis. More than 100 …
protein and lipid glycosylation and glycosylphosphatidylinositol synthesis. More than 100 …
Function over form: modeling groups of inherited neurological conditions in zebrafish
RA Kozol, AJ Abrams, DM James, E Buglo… - Frontiers in molecular …, 2016 - frontiersin.org
Zebrafish are a unique cell to behavior model for studying the basic biology of human
inherited neurological conditions. Conserved vertebrate genetics and optical transparency …
inherited neurological conditions. Conserved vertebrate genetics and optical transparency …