To build a synapse: signaling pathways in neuromuscular junction assembly

H Wu, WC Xiong, L Mei - Development, 2010 - journals.biologists.com
Synapses, as fundamental units of the neural circuitry, enable complex behaviors. The
neuromuscular junction (NMJ) is a synapse type that forms between motoneurons and …

Many paths to synaptic specificity

JR Sanes, M Yamagata - Annual Review of Cell and …, 2009 - annualreviews.org
The most impressive structural feature of the nervous system is the specificity of its synaptic
connections. Even after axons have navigated long distances to reach target areas, they …

LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction

SD Weatherbee, KV Anderson, LA Niswander - 2006 - journals.biologists.com
Low-density lipoprotein receptor-related protein 4 (Lrp4) is a member of a family of
structurally related, single-pass transmembrane proteins that carry out a variety of functions …

Synaptic input and Ca2+ activity in zebrafish oligodendrocyte precursor cells contribute to myelin sheath formation

J Li, TG Miramontes, T Czopka, KR Monk - Nature Neuroscience, 2024 - nature.com
In the nervous system, only one type of neuron–glial synapse is known to exist: that between
neurons and oligodendrocyte precursor cells (OPCs), yet their composition, assembly …

Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost

TT Kummer, T Misgeld, JR Sanes - Current opinion in neurobiology, 2006 - Elsevier
Studies of the vertebrate skeletal neuromuscular junction led to an influential model of how
neurotransmitter receptors accumulate in the postsynaptic membrane. In this model, motor …

Synaptic vulnerability in neurodegenerative disease

TM Wishart, SH Parson… - … of Neuropathology & …, 2006 - academic.oup.com
Recent developments in our understanding of the pathophysiological mechanisms
underlying degeneration in both the central and peripheral nervous systems have …

Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor

L Jing, JL Lefebvre, LR Gordon, M Granato - Neuron, 2009 - cell.com
Early during neuromuscular development, acetylcholine receptors (AChRs) accumulate at
the center of muscle fibers, precisely where motor growth cones navigate and synapses …

Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction

N Singhal, PT Martin - Developmental neurobiology, 2011 - Wiley Online Library
The vertebrate neuromuscular junction (NMJ) remains the best‐studied model for
understanding the mechanisms involved in synaptogenesis, due to its relatively large size …

CDG therapies: from bench to bedside

S Brasil, C Pascoal, R Francisco… - International journal of …, 2018 - mdpi.com
Congenital disorders of glycosylation (CDG) are a group of genetic disorders that affect
protein and lipid glycosylation and glycosylphosphatidylinositol synthesis. More than 100 …

Function over form: modeling groups of inherited neurological conditions in zebrafish

RA Kozol, AJ Abrams, DM James, E Buglo… - Frontiers in molecular …, 2016 - frontiersin.org
Zebrafish are a unique cell to behavior model for studying the basic biology of human
inherited neurological conditions. Conserved vertebrate genetics and optical transparency …