Forced and voluntary exercise differentially affect brain and behavior

JL Leasure, M Jones - Neuroscience, 2008 - Elsevier
The potential of physical exercise to decrease body weight, alleviate depression, combat
aging and enhance cognition has been well-supported by research studies. However …

Oral gavage in rats: animal welfare evaluation

PV Turner, E Vaughn… - Journal of the …, 2012 - ingentaconnect.com
The effect of chronic daily orogastric gavage with water (5 mL/kg) on behavior and
physiology was evaluated in male Sprague–Dawley rats. Treatment groups included …

Differential response of hippocampal subregions to stress and learning

DF Hawley, K Morch, BR Christie, JL Leasure - PloS one, 2012 - journals.plos.org
The hippocampus has two functionally distinct subregions–the dorsal portion, primarily
associated with spatial navigation, and the ventral portion, primarily associated with anxiety …

Gradual restraint habituation for awake functional magnetic resonance imaging combined with a sparse imaging paradigm reduces motion artifacts and stress levels …

G Russo, X Helluy, M Behroozi… - Frontiers in …, 2021 - frontiersin.org
Functional magnetic resonance imaging, as a non-invasive technique, offers unique
opportunities to assess brain function and connectivity under a broad range of applications …

Comparison of blood sampling methods for plasma corticosterone measurements in mice associated with minimal stress-related artefacts

S Kim, D Foong, MS Cooper, MJ Seibel, H Zhou - Steroids, 2018 - Elsevier
Accurate measurement of circulating glucocorticoid concentrations in rodents is often
hampered by the stress-related activation of the hypothalamic-pituitaryadrenal axis during …

Various exercise intensities differentially regulate GAP-43 and CAP-1 expression in the rat hippocampus

M Rahmati, A Kazemi - Gene, 2019 - Elsevier
Exercise intensity is known to affect neuroplasticity. Although corticosterone and lactate
levels have been linked to neuroplasticity, the effect of different endurance exercise intensity …

Acclimation and blood sampling: Effects on stress markers in C57Bl/6J mice

N Marin, A Moragon, D Gil, F Garcia-Garcia, V Bisbal - Animals, 2023 - mdpi.com
Simple Summary Blood sampling from laboratory animals is a routine procedure in
biomedical research, and husbandry is known to affect the quality of animal models. The …

Analytic and interpretational pitfalls to measuring fecal corticosterone metabolites in laboratory rats and mice

NE Rowland, LA Toth - Comparative medicine, 2019 - ingentaconnect.com
Minimization and alleviation of stress are generally viewed as desirable aspects of
laboratory animal management and use. However, achieving that goal requires an …

Region‐specific response of the hippocampus to chronic unpredictable stress

DF Hawley, JL Leasure - Hippocampus, 2012 - Wiley Online Library
The objective of the present study was to determine whether chronic unpredictable stress
(CUS) would induce hippocampal neuroplasticity in a region‐specific manner. Recent …

Non-invasive cortisol measurements as indicators of physiological stress responses in guinea pigs

M Nemeth, E Pschernig, B Wallner, E Millesi - PeerJ, 2016 - peerj.com
Non-invasive measurements of glucocorticoid (GC) concentrations, including cortisol and
corticosterone, serve as reliable indicators of adrenocortical activities and physiological …