Application of lectin microarrays for biomarker discovery

K Dang, W Zhang, S Jiang, X Lin, A Qian - ChemistryOpen, 2020 - Wiley Online Library
Many proteins in living organisms are glycosylated. As their glycan patterns exhibit protein‐,
cell‐, and tissue‐specific heterogeneity, changes in the glycosylation levels could serve as …

Recent advances in analytical approaches for glycan and glycopeptide quantitation

DG Delafield, L Li - Molecular & Cellular Proteomics, 2021 - ASBMB
Growing implications of glycosylation in physiological occurrences and human disease have
prompted intensive focus on revealing glycomic perturbations through absolute and relative …

Quantitative profiling of protein carbonylations in ferroptosis by an aniline-derived probe

Y Chen, Y Liu, T Lan, W Qin, Y Zhu, K Qin… - Journal of the …, 2018 - ACS Publications
Ferroptosis is a regulated form of necrotic cell death implicated in carcinogenesis and
neurodegeneration that is driven by phospholipid peroxidation. Lipid-derived electrophiles …

Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5

J Wu, Z Tan, H Li, M Lin, Y Jiang, L Liang… - Journal of Pineal …, 2021 - Wiley Online Library
Melatonin helps to maintain circadian rhythm, exerts anticancer activity, and plays key roles
in regulation of glucose homeostasis and energy metabolism. Glycosylation, a form of …

Cancer glycan epitopes: biosynthesis, structure and function

OMT Pearce - Glycobiology, 2018 - academic.oup.com
Aberrant glycan epitopes are a classic hallmark of malignant transformation, yet their full
clinical potential in cancer diagnostics and therapeutics is yet to be realized. This is partly …

Comprehensive overview of COVID‐19 based on current evidence

Y Kang, S Xu - Dermatologic therapy, 2020 - Wiley Online Library
In December 2019, twenty‐seven pneumonia patients with unknown causes originated in
South China seafood market in Wuhan. The virus infection spread rapidly and swept through …

Sialidase NEU1 suppresses progression of human bladder cancer cells by inhibiting fibronectin-integrin α5β1 interaction and Akt signaling pathway

X Zhou, Y Zhai, C Liu, G Yang, J Guo, G Li… - Cell Communication and …, 2020 - Springer
Background Sialic acids are widely distributed in animal tissues, and aberrantly expressed
in a variety of cancer types. High expression of sialic acid contributes to tumor …

[HTML][HTML] Trends in oligomannosylation and α1, 2-mannosidase expression in human cancers

S Chatterjee, J Ugonotti, LY Lee, A Everest-Dass… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Aberrant protein glycosylation is a prominent cancer feature. While many tumour-associated
glycoepitopes have been reported, advances in glycoanalytics continue to uncover new …

Bladder cancer cells interaction with lectin-coated surfaces under static and flow conditions

R Szydlak, IH Øvreeide, M Luty, T Zieliński… - International Journal of …, 2023 - mdpi.com
Aberrant expression of glycans, ie, oligosaccharide moiety covalently attached to proteins or
lipids, is characteristic of various cancers, including urothelial ones. The binding of lectins to …

Lectin microarrays for glycoproteomics: an overview of their use and potential

H Yu, J Shu, Z Li - Expert Review of Proteomics, 2020 - Taylor & Francis
Introduction: Glycoproteomics is an important subdiscipline of proteomics, focusing on the
role of protein glycosylation in various biological processes. Protein glycosylation is the …