The treatment of rheumatoid arthritis using Chinese medicinal plants: from pharmacology to potential molecular mechanisms

S Lü, Q Wang, G Li, S Sun, Y Guo, H Kuang - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a common worldwide public
health problem. Traditional Chinese Medicine (TCM) achieved some results to some extent …

Polyphenols in the prevention and treatment of periodontal disease: A systematic review of in vivo, ex vivo and in vitro studies

K Bunte, A Hensel, T Beikler - Fitoterapia, 2019 - Elsevier
Plant-derived polyphenols with antimicrobial and immunomodulatory characteristics appear
to provide a variety of oral health benefits. Thus, the aim of the present study was to review …

Ferulic acid, a dietary polyphenol suppresses osteoclast differentiation and bone erosion via the inhibition of RANKL dependent NF-κB signalling pathway

HM Doss, S Samarpita, R Ganesan, M Rasool - Life sciences, 2018 - Elsevier
Aims Bone erosion induced by enhanced osteoclast formation is a debilitating pathological
phenomenon in rheumatoid arthritis (RA). Recent finding has revealed that ferulic acid is …

New insights into the tonifying kidney-yin herbs and formulas for the treatment of osteoporosis

JB He, MH Chen, DK Lin - Archives of osteoporosis, 2017 - Springer
Osteoporosis is characterized by an increasing osseous fragility and fracture resulting from
the low mass and deteriorated microarchitecture in the bone tissue. The hormone …

Chinese Herbal Medicines for Rheumatoid Arthritis: Text‐Mining the Classical Literature for Potentially Effective Natural Products

X Xia, BH May, AL Zhang, X Guo, C Lu… - Evidence‐Based …, 2020 - Wiley Online Library
Background. Rheumatoid arthritis (RA) is an autoimmune disease characterized by
multijoint swelling, pain, and destruction of the synovial joints. Treatments are available but …

Discovery of a Potent Antiosteoporotic Drug Molecular Scaffold Derived from Angelica sinensis and Its Bioinspired Total Synthesis

J Zou, ZC Qiu, QQ Yu, JM Wu, YH Wang… - ACS Central …, 2024 - ACS Publications
Angelica sinensis, commonly known as Dong Quai in Europe and America and as Dang-gui
in China, is a medicinal plant widely utilized for the prevention and treatment of …

The role of Chinese herbal medicine in the management of adverse drug reactions of leflunomide in treating rheumatoid arthritis

W Wang, H Zhou, L Liu - Phytomedicine, 2020 - Elsevier
Background The high discontinuation rate in RA patients who use LEF might be attributed to
their intolerance rather than irresponsibility. The concomitant administration of Leflunomide …

Traditional Chinese decoction Si Zhi Wan attenuates ovariectomy (OVX)-induced bone loss by inhibiting osteoclastogenesis and promoting apoptosis of mature …

Q He, K Fu, H Yao, S Wei, L Xiang, S Liu… - Frontiers in …, 2022 - frontiersin.org
Si Zhi Wan (SZW) is a traditional Chinese decoction used for osteoporosis treatment.
Currently, the effect of SZW on ovariectomy (OVX)-induced bone loss and the underlying …

Study of intercellular adhesion molecule-1 (ICAM-1) in bone homeostasis

L Kong, X Yang - Current Drug Targets, 2020 - ingentaconnect.com
Although studies have established the role of integrins in bone homeostasis, especially in
osteoclastogenesis, and these molecules are novel and promising therapeutic drug targets …

MiRNA‐199a‐5p positively regulated RANKL‐induced osteoclast differentiation by target Mafb protein

K Guo, D Zhang, H Wu, Q Zhu… - Journal of Cellular …, 2019 - Wiley Online Library
MicroRNAs are involved in osteoclast differentiation. Although miR‐199a‐5p plays an
important role in many different systems and diseases, its function during …