Nanobodies: next generation of cancer diagnostics and therapeutics

EY Yang, K Shah - Frontiers in Oncology, 2020 - frontiersin.org
The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …

Current state of breast cancer diagnosis, treatment, and theranostics

A Bhushan, A Gonsalves, JU Menon - Pharmaceutics, 2021 - mdpi.com
Breast cancer is one of the leading causes of cancer-related morbidity and mortality in
women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

[PDF][PDF] Nanobody—A versatile tool for cancer diagnosis and therapeutics

M Liu, L Li, D Jin, Y Liu - Wiley Interdisciplinary Reviews …, 2021 - researchgate.net
In spite of the successful use of monoclonal antibodies (mAbs) in clinic for tumor treatment,
their applications are still hampered in therapeutic development due to limitations, such as …

Polymeric micelles: A novel drug delivery system for the treatment of breast cancer

A Chaudhuri, K Ramesh, DN Kumar, D Dehari… - Journal of Drug Delivery …, 2022 - Elsevier
Polymeric micelles have acquired quite an interest as an innovative drug delivery system for
the diagnosis and treatment of breast cancer, as they endeavour numerous benefits over the …

Current understandings and clinical translation of nanomedicines for breast cancer therapy

Y Jiang, Z Jiang, M Wang, L Ma - Advanced drug delivery reviews, 2022 - Elsevier
Breast cancer is one of the most frequently diagnosed cancers that is threatening women's
life. Current clinical treatment regimens for breast cancer often involve neoadjuvant and …

The application of inorganic nanoparticles in molecular targeted cancer therapy: EGFR targeting

M Sun, T Wang, L Li, X Li, Y Zhai, J Zhang… - Frontiers in …, 2021 - frontiersin.org
Epidermal growth factor receptor (EGFR) is an anticancer drug target for a number of
cancers, such as non-small cell lung cancer. However, unsatisfying treatment effects, terrible …

Novel targeted pH-responsive drug delivery systems based on PEGMA-modified bimetallic Prussian blue analogs for breast cancer chemotherapy

Q Chen, X Huang, G Zhang, J Li, Y Liu, X Yan - RSC advances, 2023 - pubs.rsc.org
The development of novel nanoparticle-based drug delivery systems (nano-DDSs) with high
loading capacity, low toxicity, precise targeting, and excellent biocompatibility remains …

Preclinical cancer theranostics—from nanomaterials to clinic: the missing link

KK Johnson, P Koshy, JL Yang… - Advanced Functional …, 2021 - Wiley Online Library
Nanomaterials with cancer‐imaging and therapeutic properties have emerged as the
principal focus of nanotheranostics. The past decade has experienced a significant increase …