Phages differ substantially in the bacterial hosts that they infect. Their host range is
determined by the specific structures that they use to target bacterial cells. Tailed phages …

Bacteriophages (phages), as natural antibacterial agents, are being rediscovered because
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …

Bacteriophages are the most abundant biological entity on earth, acting as the predators
and evolutionary drivers of bacteria. Owing to their inherent ability to specifically infect and …

The first stages of productive bacteriophage infections of bacterial host cells require efficient
adsorption to the cell surface followed by ejection of phage DNA into the host cytoplasm. To …

Highlights•Phages use structurally diverse receptor binding proteins (RBPs) to target
different cell wall structures.•RBPs play a critical role in spatial and temporal positioning of …

Discovery of clustered, regularly interspaced, short palindromic repeats and the Cas9 RNA-
guided nuclease (CRISPR/Cas9) system provides a new opportunity to create …

The tailed double-stranded DNA bacteriophages, or Caudovirales, constitute~ 96% of all the
known phages. Although these phages come in a great variety of sizes and morphology …

Abstract In 2016, a 68-year-old patient with a disseminated multidrug-resistant Acinetobacter
baumannii infection was successfully treated using lytic bacteriophages. Here we report the …

Bacteriophage T4 is the most well-studied member of Myoviridae, the most complex family of
tailed phages. T4 assembly is divided into three independent pathways: the head, the tail …

Wastewater is discarded from several sources, including industry, livestock, fertilizer
application, and municipal waste. If the disposed of wastewater has not been treated and …