Disease manifestations and pathogenic mechanisms of group A Streptococcus
MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - Am Soc Microbiol
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
Bacterial plasminogen receptors: mediators of a multifaceted relationship
ML Sanderson-Smith, DMP De Oliveira… - BioMed Research …, 2012 - Wiley Online Library
Multiple species of bacteria are able to sequester the host zymogen plasminogen to the cell
surface. Once localised to the bacterial surface, plasminogen can act as a cofactor in …
surface. Once localised to the bacterial surface, plasminogen can act as a cofactor in …
Plasminogen alleles influence susceptibility to invasive aspergillosis
AK Zaas, G Liao, JW Chien, C Weinberg, D Shore… - PLoS …, 2008 - journals.plos.org
Invasive aspergillosis (IA) is a common and life-threatening infection in
immunocompromised individuals. A number of environmental and epidemiologic risk factors …
immunocompromised individuals. A number of environmental and epidemiologic risk factors …
[HTML][HTML] Pathogenesis of group A streptococcal infections
A Henningham, TC Barnett, PG Maamary… - Discovery …, 2012 - discoverymedicine.com
Group A Streptococcus (GAS; Streptococcus pyogenes) is a human pathogen which causes
significant morbidity and mortality globally. GAS typically infects the throat and skin of the …
significant morbidity and mortality globally. GAS typically infects the throat and skin of the …
A processed multidomain Mycoplasma hyopneumoniae adhesin binds fibronectin, plasminogen, and swine respiratory cilia
Porcine enzootic pneumonia is a chronic respiratory disease that affects swine. The
etiological agent of the disease, Mycoplasma hyopneumoniae, is a bacterium that adheres …
etiological agent of the disease, Mycoplasma hyopneumoniae, is a bacterium that adheres …
Repeat regions R1 and R2 in the P97 paralogue Mhp271 of Mycoplasma hyopneumoniae bind heparin, fibronectin and porcine cilia
AT Deutscher, C Jenkins, FC Minion… - Molecular …, 2010 - Wiley Online Library
Mycoplasma hyopneumoniae, the causative agent of porcine enzootic pneumonia, adheres
to ciliated respiratory epithelia resulting in ciliostasis and epithelial cell death. The cilium …
to ciliated respiratory epithelia resulting in ciliostasis and epithelial cell death. The cilium …
Differing efficacies of lead group A streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models
ABSTRACT Group A Streptococcus (GAS) is an important human pathogen responsible for
both superficial infections and invasive diseases. Autoimmune sequelae may occur upon …
both superficial infections and invasive diseases. Autoimmune sequelae may occur upon …
Streptolysin O accelerates the conversion of plasminogen to plasmin
Abstract Group A Streptococcus (GAS) is a human-specific bacterial pathogen that can
exploit the plasminogen-plasmin fibrinolysis system to dismantle blood clots and facilitate its …
exploit the plasminogen-plasmin fibrinolysis system to dismantle blood clots and facilitate its …
Conserved anchorless surface proteins as group A streptococcal vaccine candidates
Streptococcus pyogenes (group A Streptococcus (GAS)) causes∼ 700 million human
infections each year, resulting in over 500,000 deaths. The development of a commercial …
infections each year, resulting in over 500,000 deaths. The development of a commercial …
The plasminogen-binding group A streptococcal M protein-related protein Prp binds plasminogen via arginine and histidine residues
The migration of the human pathogen Streptococcus pyogenes (group A streptococcus) from
localized to deep tissue sites may result in severe invasive disease, and sequestration of the …
localized to deep tissue sites may result in severe invasive disease, and sequestration of the …