Microbial whole-cell biosensors: Current applications, challenges, and future perspectives

M Moraskie, MHO Roshid, G O'Connor, E Dikici… - Biosensors and …, 2021 - Elsevier
Abstract Microbial Whole-Cell Biosensors (MWCBs) have seen rapid development with the
arrival of 21st century biological and technological capabilities. They consist of microbial …

Use of whole-cell bioreporters to assess bioavailability of contaminants in aquatic systems

Y Zhu, E Elcin, M Jiang, B Li, H Wang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Water contamination has become increasingly a critical global environmental issue that
threatens human and ecosystems' health. Monitoring and risk assessment of toxic pollutants …

De Novo Design of the ArsR Regulated Pars Promoter Enables a Highly Sensitive Whole-Cell Biosensor for Arsenic Contamination

SY Chen, Y Zhang, R Li, B Wang, BC Ye - Analytical Chemistry, 2022 - ACS Publications
Whole-cell biosensors for arsenic contamination are typically designed based on natural
bacterial sensing systems, which are often limited by their poor performance for precisely …

Electropositive far-ultraviolet carbon nanoparticles-based photoluminescent photoinduced-electron transfer sensor for sodium dodecyl sulfate and sodium lauryl …

L Hu, XQ Li, YL Jia, MJ Wei, HY Li, FY Kong, W Wang… - Dyes and …, 2023 - Elsevier
Unrestrained use of sodium dodecyl sulfate (SDS) and sodium lauryl sulfonate (SLS) in
industry, agriculture and household are causing its subsequent accumulation in waterways …

Directed evolution of linker helix as an efficient strategy for engineering LysR-type transcriptional regulators as whole-cell biosensors

W Pu, J Chen, P Liu, J Shen, N Cai, B Liu, Y Lei… - Biosensors and …, 2023 - Elsevier
Whole-cell biosensors based on transcriptional regulators are powerful tools for rapid
measurement, high-throughput screening, dynamic metabolic regulation, etc. To optimize …

An engineered quorum-sensing-based whole-cell biosensor for active degradation of organophosphates

J He, X Zhang, Y Qian, Q Wang, Y Bai - Biosensors and Bioelectronics, 2022 - Elsevier
The environmental accumulation of organophosphates is a serious threat to public health.
To detect these xenobiotics, a broad range of sensors has been developed in past decades …

Superwettable interface towards biodetection in confined space

Z Pang, Z Cao, W Li, W Xu, Y Zhang, Q Zhou, J Pan… - Nano Research, 2024 - Springer
The detection of biomarkers with both high sensitivity and specificity is crucial for the
diagnosis and treatment of related diseases. However, many current detections employ ex …

Transcription Factor-Based Biosensors for Detecting Pathogens

Y Jeon, Y Lee, K Kim, G Jang, Y Yoon - Biosensors, 2022 - mdpi.com
Microorganisms are omnipresent and inseparable from our life. Many of them are beneficial
to humans, while some are not. Importantly, foods and beverages are susceptible to …

De novo design of a transcription factor for a progesterone biosensor

K Liu, Y Zhang, K Liu, Y Zhao, B Gao, X Tao… - Biosensors and …, 2022 - Elsevier
Identifying, isolating, and obtaining naturally occurring transcription factors (TFs) is crucial
for developing transcription-dependent biosensors. However, identifying and optimizing TFs …

Application Evaluation and Performance-Directed Improvement of the Native and Engineered Biosensors

M Li, Z Chen, YX Huo - ACS sensors, 2024 - ACS Publications
Transcription factor (TF)-based biosensors (TFBs) have received considerable attention in
various fields due to their capability of converting biosignals, such as molecule …