Antibacterial fluoroquinolones (FQs) are frequently used in treating infections. However, the
value of FQs is debatable due to their association with severe adverse effects (AEs). The …

Aims The risk, characteristics, and outcome of out-of-hospital cardiac arrest (OHCA) in
patients with congenital heart disease (CHD) remain scarcely investigated. Methods and …

Fluoroquinolone associated toxicity after along-term fluoroquinolone antibiotic therapy
appears as a significant medical and social problem. The objective of this review was mainly …

Quinolone antibiotics (norfloxacin) pose a serious threat to animal and human health due to
their misuse and difficulty in being broken down in surface water and food. Rapid and …

Aguayo-Orozco et al.[1] report survival differences in patients taking renin-angiotensin
system inhibitors depending on the drug prescription trajectories identified through Danish …

Sensitive and selective detection of fluoroquinolones, especially from different sources, is
challenging. This study reported an uncommon three-cage lanthanide metal-organic …

Biological plausibility suggests that fluoroquinolones may lead to mitral valve regurgitation
or aortic valve regurgitation (MR/AR) through a collagen degradation pathway. However …

Background Recently, there have been conflicting results reporting an increased risk of AR
or MR associated with oral fluoroquinolones (FQs). This study investigated whether the use …

Highlights Using nationwide Danish health register data, associations between
fluoroquinolone use and elevated hazard rates of Achilles tendon rupture were found …

Fluoroquinolones are among the most commonly prescribed antimicrobial agents that target
two essential bacterial type II topoisomerases, DNA gyrase and topoisomerase IV, and …