Biocompatible polymer materials: role of protein–surface interactions
H Chen, L Yuan, W Song, Z Wu, D Li - Progress in Polymer Science, 2008 - Elsevier
Biocompatibility is one of the most important characteristics of a biomedical polymer material
whose surface is required to interact with a biological system. Such interactions between …
whose surface is required to interact with a biological system. Such interactions between …
Blood-compatible biomaterials by surface coating with a novel antithrombin–heparin covalent complex
P Klement, YJ Du, L Berry, M Andrew, AKC Chan - Biomaterials, 2002 - Elsevier
Covalent antithrombin–heparin complex (ATH) was covalently grafted to a polycarbonate
urethane (Corethane®) endoluminal graft (a kind gift of Corvita Corporation) after being …
urethane (Corethane®) endoluminal graft (a kind gift of Corvita Corporation) after being …
[图书][B] Polymeric Biomaterials: Medicinal and Pharmaceutical Applications, Volume 2
S Dumitriu, V Popa - 2013 - books.google.com
The third edition of a bestseller, this substantially expanded reference, now in two volumes,
presents the latest polymer developments and most up-to-date applications of polymeric …
presents the latest polymer developments and most up-to-date applications of polymeric …
Covalent antithrombin–heparin complexes
Unfractionated heparin (UFH) and low molecular weight heparin (LMWH) have been utilized
as primary anticoagulants for thrombosis prophylaxis and treatment. However, a number of …
as primary anticoagulants for thrombosis prophylaxis and treatment. However, a number of …
Binding of heparin to plasma proteins and endothelial surfaces is inhibited by covalent linkage to antithrombin
AKC Chan, N Paredes, B Thong… - Thrombosis and …, 2004 - thieme-connect.com
Unfractionated heparin (UFH) and low molecular weight heparin (LMWH) are used for
prophylaxis and treatment of thrombosis. However, UFH has a short plasma half-life and …
prophylaxis and treatment of thrombosis. However, UFH has a short plasma half-life and …
In vivo rabbit acute model tests of polyurethane catheters coated with a novel antithrombin-heparin covalent complex
YJ Du, P Klement, LR Berry, P Tressel… - Thrombosis and …, 2005 - thieme-connect.com
Catheter use has been associated with an incresed risk of thrombotic complications. The
objective was to make catheters less thrombogenic with the use of antithrombin-heparin …
objective was to make catheters less thrombogenic with the use of antithrombin-heparin …
Inhibition of plasmin generation in plasma by heparin, low molecular weight heparin, and a covalent antithrombin–heparin complex
GMT Chang, HM Atkinson, LR Berry… - Blood Coagulation & …, 2017 - journals.lww.com
The clinical limitations of unfractionated heparin (UFH) and low molecular weight heparin
(LMWH) led to the development of an antithrombin–heparin covalent complex (ATH), which …
(LMWH) led to the development of an antithrombin–heparin covalent complex (ATH), which …
Inhibition of fibrin-bound thrombin by a covalent antithrombin-heparin complex
LR Berry, DL Becker, AKC Chan - The journal of biochemistry, 2002 - academic.oup.com
Numerous studies have shown that fibrin-bound thrombin (IIa) is proteched from inhibition
by antithrombin (AT)+ heparin (II) due to the formation if R ternary fibrin. IIa. H complex of AT …
by antithrombin (AT)+ heparin (II) due to the formation if R ternary fibrin. IIa. H complex of AT …
Anticoagulant mechanisms of covalent antithrombin-heparin investigated by thrombelastography
HM Atkinson, TA Mewhort-Buist… - Thrombosis and …, 2009 - thieme-connect.com
We have developed an antithrombin-heparin covalent complex (ATH) which inhibits
coagulation enzymes by two mechanisms: directly, or by catalytic activation of plasma …
coagulation enzymes by two mechanisms: directly, or by catalytic activation of plasma …