Evidence for incentive salience sensitization as a pathway to alcohol use disorder

RU Cofresí, BD Bartholow, TM Piasecki - Neuroscience & Biobehavioral …, 2019 - Elsevier
The incentive salience sensitization (ISS) theory of addiction holds that addictive behavior
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …

Electrochemistry at the Synapse

M Shin, Y Wang, JR Borgus… - Annual Review of …, 2019 - annualreviews.org
Electrochemical measurements of neurotransmitters provide insight into the dynamics of
neurotransmission. In this review, we describe the development of electrochemical …

[图书][B] Alcohol: Neurobiology of Addiction

GF Koob, MA Arends, ML McCracken, M Le Moal - 2021 - books.google.com
A current survey and synthesis of the most important findings in our understanding of the
neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series …

Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review

AA Vena, SL Zandy, RU Cofresí… - Pharmacology & …, 2020 - Elsevier
Alcohol use disorder has multiple characteristics including excessive ethanol consumption,
impaired control over drinking behaviors, craving and withdrawal symptoms, compulsive …

Instrumental and Pavlovian mechanisms in alcohol use disorder

N Doñamayor, C Ebrahimi, M Garbusow… - Current Addiction …, 2021 - Springer
Abstract Purpose of Review Current theories of alcohol use disorders (AUD) highlight the
importance of Pavlovian and instrumental learning processes mainly based on preclinical …

Acute depletion of dopamine precursors in the human brain: effects on functional connectivity and alcohol attentional bias

A Elton, ML Faulkner, DL Robinson… - …, 2021 - nature.com
Individuals who abuse alcohol often show exaggerated attentional bias (AB) towards
alcohol-related cues, which is thought to reflect reward conditioning processes. Rodent …

Stimuli predicting high-calorie reward increase dopamine release and drive approach to food in the absence of homeostatic need

A Gómez-A, TA Shnitko, KL Caref, SM Nicola… - Nutritional …, 2022 - Taylor & Francis
Animals and humans are motivated to consume high-fat, high-calorie foods by cues
predicting such foods. The neural mechanisms underlying this effect are not well …

Ampicillin/sulbactam treatment modulates NMDA receptor NR2B subunit and attenuates neuroinflammation and alcohol intake in male high alcohol drinking rats

F Alasmari, H Alhaddad, W Wong, RL Bell, Y Sari - Biomolecules, 2020 - mdpi.com
Exposure to ethanol commonly manifests neuroinflammation. Beta (β)-lactam antibiotics
attenuate ethanol drinking through upregulation of astroglial glutamate transporters …

Recruitment and disruption of ventral pallidal cue encoding during alcohol seeking

DJ Ottenheimer, K Wang, A Haimbaugh… - European Journal of …, 2019 - Wiley Online Library
A critical area of inquiry in the neurobiology of alcohol abuse is the mechanism by which
cues gain the ability to elicit alcohol use. Previously, we found that cue‐evoked activity in rat …

Endogenous opiates and behavior: 2018

RJ Bodnar - Peptides, 2020 - Elsevier
This paper is the forty-first consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …