Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

Neuronal migration in the cortex is controlled by the paracrine action of the classical
neurotransmitters glutamate and GABA. Glutamate controls radial migration of pyramidal …

Granule cell migration influences the laminar structure of the cerebellum and thereby affects
cerebellum function. Bergmann glia are derived from radial glial cells and aid in granule cell …

Brain development encompasses a number of processes including synaptogenesis,
migration and synaptic plasticity. These activities are regulated by neurotransmitter …

Our review suggests that most autism spectrum disorder (ASD) risk factors are connected,
either directly or indirectly, to immunoexcitotoxicity. Chronic brain inflammation is known to …

NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development.
Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These …

Perfluoroalkyl acids (PFAAs) are persistent compounds used in many industrial as well as
consumer products. Despite restrictions, these compounds are found at measurable …

NMDA receptors (NMDARs) are critical to the development of the nervous system, although
their roles at axonal growth cones are unclear. We examined NMDAR localization and …

Exposure to persistent organic pollutants (POPs), encompassing chlorinated (Cl),
brominated (Br) and perfluoroalkyl acid (PFAA) compounds is associated with adverse …

NMDA type glutamate receptors (NMDARs) are best known for their role in synaptogenesis
and synaptic plasticity. Much less is known about their developmental role before neurons …