Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins
S Suetsugu, S Kurisu, T Takenawa - Physiological reviews, 2014 - journals.physiology.org
All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
Regulation of invadopodia by the tumor microenvironment
CM Gould, SA Courtneidge - Cell adhesion & migration, 2014 - Taylor & Francis
The tumor microenvironment consists of stromal cells, extracellular matrix (ECM), and
signaling molecules that communicate with cancer cells. As tumors grow and develop, the …
signaling molecules that communicate with cancer cells. As tumors grow and develop, the …
Protein dynamics at invadopodia control invasion–migration transitions in melanoma cells
M Legrand, A Mousson, P Carl, L Rossé… - Cell Death & …, 2023 - nature.com
Cell invasion is a highly complex process that requires the coordination of cell migration and
degradation of the extracellular matrix. In melanoma cells, as in many highly invasive cancer …
degradation of the extracellular matrix. In melanoma cells, as in many highly invasive cancer …
N-wasp is essential for the negative regulation of B cell receptor signaling
C Liu, X Bai, J Wu, S Sharma, A Upadhyaya… - PLoS …, 2013 - journals.plos.org
Negative regulation of receptor signaling is essential for controlling cell activation and
differentiation. In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) …
differentiation. In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) …
Excitable networks controlling cell migration during development and disease
The directed movements of individual, groups, or sheets of cells at specific times in particular
locations bring about form and complexity to developing organisms. Cells move by …
locations bring about form and complexity to developing organisms. Cells move by …
The role and regulation of Rab40b–Tks5 complex during invadopodia formation and cancer cell invasion
A Jacob, E Linklater, BA Bayless… - Journal of cell …, 2016 - journals.biologists.com
Invadopodia formation and extracellular matrix degradation are key events during cancer
cell invasion, yet little is known about mechanisms mediating these processes. Here, we …
cell invasion, yet little is known about mechanisms mediating these processes. Here, we …
The regulators of BCR signaling during B cell activation
Y Wen, Y Jing, L Yang, D Kang, P Jiang, N Li… - Blood Science, 2019 - mednexus.org
B lymphocytes produce antibodies under the stimulation of specific antigens, thereby
exerting an immune effect. B cells identify antigens by their surface B cell receptor (BCR) …
exerting an immune effect. B cells identify antigens by their surface B cell receptor (BCR) …
[HTML][HTML] Membrane lipids in invadopodia and podosomes: key structures for cancer invasion and metastasis
H Yamaguchi, T Oikawa - Oncotarget, 2010 - ncbi.nlm.nih.gov
Invadopodia are extracellular matrix (ECM)-degrading protrusions formed by invasive
cancer cells. Podosomes are structures functionally similar to invadopodia that are found in …
cancer cells. Podosomes are structures functionally similar to invadopodia that are found in …
[HTML][HTML] Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation
E Hoekstra, AM Das, M Willemsen, M Swets… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the second most common cause of cancer-related death,
encouraging the search for novel therapeutic targets affecting tumor cell proliferation and …
encouraging the search for novel therapeutic targets affecting tumor cell proliferation and …
[图书][B] Encyclopedia of signaling molecules
S Choi - 2012 - researchgate.net
P-Rex1 (PIP3-dependent Rac exchanger 1, PREX1) is a Dbl-type guanine-nucleotide
exchange factor (GEF) that activates Rac-like small G proteins (small GTPases). P-Rex1 was …
exchange factor (GEF) that activates Rac-like small G proteins (small GTPases). P-Rex1 was …