Rotational thromboelastometry (ROTEM) is a point-of-care viscoelastic method and enables
to assess viscoelastic profiles of whole blood in various clinical settings. ROTEM-guided …

Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Background A severe mismatch between the supply and demand of oxygen is the common
feature of all types of shock. We present a newly developed, clinically oriented classification …

Objective: The aim of this study was to identify the effects of recent innovations in trauma
major hemorrhage management on outcome and transfusion practice, and to determine the …

Acute Traumatic Coagulopathy occurs immediately after massive trauma when shock,
hypoperfusion, and vascular damage are present. Mechanisms for this acute coagulopathy …

Objective: Developing pragmatic data-driven algorithms for management of trauma induced
coagulopathy (TIC) during trauma hemorrhage for viscoelastic hemostatic assays (VHAs) …

Trauma-induced coagulopathy is associated with very high mortality, and hemorrhage
remains the leading preventable cause of death after injury. Directed methods to combat …