The ability of skin to act as a barrier is primarily determined by cells that maintain the
continuity and integrity of skin and restore it after injury. Cutaneous wound healing in adult …

The basement membrane extracellular matrix contacts epithelial, endothelial, fat and smooth
muscle cells. Because this extracellular matrix is so thin, it had been hard to study its …

This review focuses on the intricate properties of the glomerular barrier. Other reviews have
focused on podocyte biology, mesangial cells, and the glomerular basement membrane …

Two major glycosaminoglycan types, heparan sulfate (HS) and chondroitin sulfate (CS),
control many aspects of development and physiology in a type-specific manner. HS and CS …

Hynda K. Kleinman,** Mary L. McGarvey, Lance A. Liotta, Pamela Gehron Robey, Karl
Tryggvason, and George R. Martin abstract: We have studied the extractability of type IV …

Corneal endothelium is the single layer of cells forming a boundary between the corneal
stroma and anterior chamber. The barrier and “pump” functions of the endothelium are …

Reciprocal interactions between epithelium and mesenchyme mediate crucial aspects of
embryonic development and direct the coordinated organogenesis, correct spatial …

Basement membranes are layers of extracellular matrix which anchor the epithelium or
endothelium to connective tissues in most organs. Descemet's membrane—which is the …

Collagen type IV, laminin, heparan sulfate proteoglycans, nidogen (entactin) and BM‐40
(osteonectin, SPARC) represent major structural proteins of basement membranes. They are …

Hereditary Proteinuria Syndromes and Mechanisms of Proteinuria | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …