Investigating the antiplasmodial activity of substituted cyclopentadienyl rhodium and iridium complexes of 2-(2-pyridyl) benzimidazole

L Jordaan, MT Ndlovu, S Mkhize, S Ngubane… - Journal of …, 2022 - Elsevier
Six cationic half-sandwich Ir (III) and Rh (III) complexes (C1-C6) were synthesised by
reaction of 2-(2-pyridyl) benzimidazole with the appropriate chloro-bridged dimers. All …

Investigation of bioorganometallic artemisinins as antiplasmodials

CC Albertyn, A van Niekerk, S Duffy, VM Avery… - Journal of …, 2023 - Elsevier
The aim of this study was to improve the activity of artemisinin-based compounds for the
treatment of malaria, primarily caused by Plasmodium falciparum. The artemisinin scaffold …

Synthesis and anticancer evaluation of trinuclear N^ N quinolyl-benzimidazole-based PGM complexes

N Msimango, A Welsh, S Prince, GS Smith - Inorganic Chemistry …, 2022 - Elsevier
The synthesis, characterization and cytotoxicity of a novel tris-benzimidazole-quinoline
hybrid ligand and its corresponding cationic trimetallic complexes are described. The …

Synthesis of ferrocenyl benzimidazole derivatives as novel anti-Toxoplasma gondii agents

MT Ndlovu, CR Harding, CH Kaschula… - New Journal of …, 2024 - pubs.rsc.org
Toxoplasmosis, a disease caused by the apicomplexan parasite Toxoplasma gondii, affects
up to one third of the global population. Although immunocompetent individuals rarely …

[HTML][HTML] Trinuclear ruthenium (II) polypyridyl complexes: Evaluation as photosensitizers for enhanced cervical cancer treatment

A Welsh, R Matshitse, SF Khan, T Nyokong… - Journal of Inorganic …, 2024 - Elsevier
Trinuclear ruthenium (II) polypyridyl complexes anchored to benzimidazole-
triazine/trisamine scaffolds were investigated as photosensitizers for photodynamic therapy …

2-Ferrocene-4-amine-1H-benzo [d] imidazole and their derivatives: Synthesis, biological and docking study

M Kawad, S Sangani, J Parmar, RC Dabhi, PS Arya… - Polyhedron, 2024 - Elsevier
An organometallic series based on 2-ferrocene-4-amine-1H-benzo [d] imidazole derivative
has been synthesized and characterized through FTIR, H/C NMR, and LCMS. Their …