Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments
DG Siedler, MI Chuah, MTK Kirkcaldie… - Frontiers in cellular …, 2014 - frontiersin.org
Traumatic brain injury (TBI) from penetrating or closed forces to the cranium can result in a
range of forms of neural damage, which culminate in mortality or impart mild to significant …
range of forms of neural damage, which culminate in mortality or impart mild to significant …
Neurofilament proteins in neurodegenerative diseases
Q Liu, F Xie, SL Siedlak, A Nunomura, K Honda… - Cellular and Molecular …, 2004 - Springer
The function of neurofilaments, the major component in large myelinated neurons, is not well
understood even though they were discovered as structures over 100 years ago. Recent …
understood even though they were discovered as structures over 100 years ago. Recent …
α-Internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS
A Yuan, MV Rao, T Sasaki, Y Chen… - Journal of …, 2006 - Soc Neuroscience
α-Internexin, a neuronal intermediate filament protein implicated in neurodegenerative
disease, coexists with the neurofilament (NF) triplet proteins (NF-L, NF-M, and NF-H) but has …
disease, coexists with the neurofilament (NF) triplet proteins (NF-L, NF-M, and NF-H) but has …
Protein accumulation in traumatic brain injury
DH Smith, K Uryu, KE Saatman, JQ Trojanowski… - Neuromolecular …, 2003 - Springer
Traumatic brain injury (TBI) is one of the most devastating diseases in our society,
accounting for a high percentage of mortality and disability. A major consequence of TBI is …
accounting for a high percentage of mortality and disability. A major consequence of TBI is …
Nusinersen treatment and cerebrospinal fluid neurofilaments: An explorative study on Spinal Muscular Atrophy type 3 patients
I Faravelli, M Meneri, D Saccomanno… - Journal of Cellular …, 2020 - Wiley Online Library
The antisense oligonucleotide Nusinersen has been recently licensed to treat spinal
muscular atrophy (SMA). Since SMA type 3 is characterized by variable phenotype and …
muscular atrophy (SMA). Since SMA type 3 is characterized by variable phenotype and …
Beyond structure: do intermediate filaments modulate cell signalling?
JM Paramio, JL Jorcano - Bioessays, 2002 - Wiley Online Library
Intermediate filament (IF) proteins form the largest family of cytoskeletal proteins in
mammalian cells. The function of these proteins has long been thought to be only structural …
mammalian cells. The function of these proteins has long been thought to be only structural …
Organophosphorus flame retardants are developmental neurotoxicants in a rat primary brainsphere in vitro model
HT Hogberg, R de Cássia da Silveira E Sá… - Archives of …, 2021 - Springer
Due to regulatory bans and voluntary substitutions, halogenated polybrominated diphenyl
ether (PBDE) flame retardants (FR) are increasingly substituted by mainly …
ether (PBDE) flame retardants (FR) are increasingly substituted by mainly …
Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations
Y Abreu-Villaça, FJ Seidler, CA Tate, TA Slotkin - Brain research, 2003 - Elsevier
In the fetus, nicotine is a neuroteratogen that elicits cell damage and loss and subsequent
abnormalities of synaptic function. We explored whether these effects extend into …
abnormalities of synaptic function. We explored whether these effects extend into …
Intrinsic disorder as a natural preservative: high levels of intrinsic disorder in proteins found in the 2600-year-old human brain
AS Mohammed, VN Uversky - Biology, 2022 - mdpi.com
Simple Summary Reported earlier, results of the proteomic analysis of the Heslington brain
(which is at least 2600-year-old brain tissue uncovered within the skull excavated in 2008 …
(which is at least 2600-year-old brain tissue uncovered within the skull excavated in 2008 …
Is spinal muscular atrophy the result of defects in motor neuron processes?
M Briese, B Esmaeili, DB Sattelle - Bioessays, 2005 - Wiley Online Library
The hereditary neurodegenerative disease spinal muscular atrophy (SMA) with childhood
onset is one of the most common genetic causes of infant mortality. The disease is …
onset is one of the most common genetic causes of infant mortality. The disease is …