Nanotools for sepsis diagnosis and treatment

L Papafilippou, A Claxton, P Dark… - Advanced …, 2021 - Wiley Online Library
Sepsis is one of the leading causes of death worldwide with high mortality rates and a
pathological complexity hindering early and accurate diagnosis. Today, laboratory culture …

Targeted extracellular vesicle delivery systems employing superparamagnetic iron oxide nanoparticles

Z Zhuo, J Wang, Y Luo, R Zeng, C Zhang, W Zhou… - Acta biomaterialia, 2021 - Elsevier
In the past decade, the study of extracellular vesicles (EVs), especially exosomes (50–150
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …

[HTML][HTML] Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy

C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …

[HTML][HTML] Nano-bio interactions: a neutrophil-centric view

S Keshavan, P Calligari, L Stella, L Fusco… - Cell Death & …, 2019 - nature.com
Neutrophils are key components of the innate arm of the immune system and represent the
frontline of host defense against intruding pathogens. However, neutrophils can also cause …

[HTML][HTML] The potential impact of nanomedicine on COVID-19-induced thrombosis

P Russell, L Esser, CE Hagemeyer… - Nature …, 2023 - nature.com
Extensive reports of pulmonary embolisms, ischaemic stroke and myocardial infarctions
caused by coronavirus disease 2019 (COVID-19), as well as a significantly increased long …

[HTML][HTML] Nanoparticle-induced immune response: Health risk versus treatment opportunity?

K Pondman, S Le Gac, U Kishore - Immunobiology, 2023 - Elsevier
Nanoparticles (NPs) are not only employed in many biomedical applications in an
engineered form, but also occur in our environment, in a more hazardous form. NPs interact …

Comprehensive in-vitro and magnetic hyperthermia investigation of biocompatible non-stoichiometric Zn0. 5Ca0. 5Fe2O4 and Mg0. 5Ca0. 5Fe2O4 nanoferrites on …

S Tiwari, P Joshi, KP Hazarika, P Seal, JP Borah… - Journal of Alloys and …, 2024 - Elsevier
In this research, the suitability and potential of two biocompatible mixed valent non-
stoichiometric spinel nanoferrites viz., Zn 0.5 Ca 0.5 Fe 2 O 4 (ZCNF) and Mg 0.5 Ca 0.5 Fe …

Influence of nanoparticles on the haemostatic balance: between thrombosis and haemorrhage

HDN Tran, SS Moonshi, ZP Xu, HT Ta - Biomaterials Science, 2022 - pubs.rsc.org
Maintenance of a delicate haemostatic balance or a balance between clotting and bleeding
is critical to human health. Irrespective of administration route, nanoparticles can reach the …

Augmenting Neutrophil Extracellular Traps with Carbonized Polymer Dots: A Potential Treatment for Bacterial Sepsis

CJ Lin, TL Hwang, RYL Wang, A Nain, RH Shih… - Small, 2024 - Wiley Online Library
Sepsis is a life‐threatening condition that can progress to septic shock as the body's extreme
response to pathogenesis damages its own vital organs. Staphylococcus aureus (S. aureus) …

[HTML][HTML] Neutrophil extracellular trap-driven occlusive diseases

KO Yaykasli, C Schauer, LE Muñoz, A Mahajan… - Cells, 2021 - mdpi.com
The enlightenment of the formation of neutrophil extracellular traps (NETs) as a part of the
innate immune system shed new insights into the pathologies of various diseases. The initial …