Impact of R-CHOP dose intensity on survival outcomes in diffuse large B-cell lymphoma: a systematic review

EJ Bataillard, CY Cheah, MJ Maurer… - Blood …, 2021 - ashpublications.org
The dilemma of whether to treat elderly patients with diffuse large B-cell lymphoma (DLBCL)
with a full or reduced dose intensity (DI) of R-CHOP (cyclophosphamide, doxorubicin …

[HTML][HTML] Role of Radiotherapy in the Management of Elderly Patients With Lymphoma

R Kumar, RR Parikh - Seminars in Radiation Oncology, 2025 - Elsevier
Lymphoma in elderly patients has unique treatment challenges due to baseline co-
morbidities, nutrition status, impairment in functional capacities and fitness. While geriatric …

[HTML][HTML] ESMO Consensus Conference on malignant lymphoma: general perspectives and recommendations for the clinical management of the elderly patient with …

C Buske, M Hutchings, M Ladetto, V Goede, U Mey… - Annals of …, 2018 - Elsevier
Abstract The European Society for Medical Oncology (ESMO) consensus conference on
mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June …

[HTML][HTML] Treatment strategies and outcomes in diffuse large B-cell lymphoma among 1011 patients aged 75 years or older: a Danish population-based cohort study

MB Juul, PH Jensen, H Engberg, S Wehberg… - European Journal of …, 2018 - Elsevier
Background Optimal treatment strategy for the oldest patients with diffuse large B-cell
lymphoma (DLBCL) remains controversial, as this group often is precluded from clinical …

Management strategies and outcomes for very elderly patients with diffuse large B‐cell lymphoma

D Chihara, JR Westin, Y Oki, MA Ahmed, B Do… - Cancer, 2016 - Wiley Online Library
BACKGROUND The number of elderly patients with diffuse large B‐cell lymphoma (DLBCL)
in our aging society continues to rise, although the optimal management of very elderly …

Diffuse large B cell lymphoma (DLBCL) in patients older than 65 years: analysis of 3 year Real World data of practice patterns and outcomes in England

L Hounsome, TA Eyre, R Ireland, A Hodson… - British journal of …, 2022 - nature.com
Background We wished to examine treatment and outcome patterns in older diffuse large B-
cell lymphoma (DLBCL) patients, with a focus on the effect of route-to-diagnosis to outcome …

A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL

KT Isaksen, MA Mastroianni, M Rinde… - Blood …, 2021 - ashpublications.org
Patients with diffuse large B-cell lymphoma (DLBCL) have a median age of 70 years. Yet,
empirical knowledge about the treatment of older patients is limited because they are …

Impact of comorbidity on disease characteristics, treatment intent and outcome in diffuse large B‐cell lymphoma: a Swedish lymphoma register study

T Wästerlid, M Mohammadi, KE Smedby… - Journal of internal …, 2019 - Wiley Online Library
Background Comorbidity impacts overall survival amongst patients with diffuse large B‐cell
lymphoma (DLBCL). However, associations of comorbidity with lymphoma characteristics …

Impact of intended and relative dose intensity of R‐CHOP in a large, consecutive cohort of elderly diffuse large B‐cell lymphoma patients treated with curative intent …

TA Eyre, N Martinez‐Calle, C Hildyard… - Journal of internal …, 2019 - Wiley Online Library
Background The increasing incidence of diffuse large B‐cell lymphoma (DLBCL) in ageing
populations places a significant burden on healthcare systems. Co‐morbidity, frailty, and …

Front-line treatment of high grade B cell non-Hodgkin lymphoma

M Kesavan, TA Eyre, GP Collins - Current Hematologic Malignancy …, 2019 - Springer
Abstract Purpose of Review Rituximab-based chemoimmunotherapy has resulted in a
marked improvement in the survival of diffuse large B cell lymphoma (DLBCL). We reflect …