Background Pulmonary hypertension (PH) is a devastating disease with poor prognosis and
high mortality. Hypoxia induced pulmonary hypertension (HPH) is a persistent threat to …

Humans are constantly exposed to low concentrations of ubiquitous environmental pollutant,
Bisphenol A (BPA). Due to the prevalence of hypertension (one of the major risk factors of …

Elevated heart rate (HR) is a well-recognized but somewhat neglected risk factor among the
healthy population and various cardiovascular pathologies (1). High HR is fraught with a …

Lactacystin is a specific proteasome inhibitor that blocks the hydrolysis of intracellular
proteins by ubiquitin/proteasome system inhibition. The administration of lactacystin to rats …

In the present study, we investigated whether curcumin administration would interfere with
the main renal features of l‐NAME‐induced hypertension model. For this purpose, we …

Hypertension is linked to hyperpolarization-activated cyclic nucleotide-gated (HCN) function,
expressed in excitable and non-excitable cells. Considering that the reduction in heart rate …

Simple Summary Chronic kidney disease is a health problem in which the kidneys cannot
function normally. Thus, they cannot filter blood effectively and cause waste accumulation in …

Abstract Ethnopharmacological relevance Tsantan Sumtang (TS), originated from the Four
Tantras, is an empirical Tibetan medicine prescription, which has been widely used for …

Introduction. Liver fibrosis is the damage repair response following chronic liver diseases.
Activated hepatic stellate cells (HSCs) are the main extracellular matrix (ECM)-producing …

There is ample evidence on the benefit of angiotensin receptor-neprilysin inhibitors (ARNIs)
in heart failure, yet data regarding the potential protective action of ARNIs in hypertensive …