Self-collimating SPECT with multi-layer interspaced mosaic detectors

T Ma, Q Wei, Z Lyu, D Zhang, H Zhang… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Conventional single photon emission computed tomography (SPECT) relies on mechanical
collimation whose resolution and sensitivity are interdependent, the best performance a …

Inclusion of quasi-vertex views in a brain-dedicated multi-pinhole SPECT system for improved imaging performance

B Auer, N Zeraatkar, JC Goding, A Könik… - Physics in Medicine …, 2021 - iopscience.iop.org
With brain-dedicated multi-detector systems employing pinhole apertures the usage of
detectors facing the top of the patient's head (ie quasi-vertex (QV) views) can provide the …

Mesh modeling of system geometry and anatomy phantoms for realistic GATE simulations and their inclusion in SPECT reconstruction

B Auer, A Könik, TJ Fromme… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Monte-Carlo simulation studies have been essential for advancing various
developments in single photon emission computed tomography (SPECT) imaging, such as …

Improvement in sampling and modulation of multiplexing with temporal shuttering of adaptable apertures in a brain-dedicated multi-pinhole SPECT system

N Zeraatkar, B Auer, KS Kalluri, M May… - Physics in Medicine …, 2021 - iopscience.iop.org
We are developing a multi-detector pinhole-based stationary brain-dedicated SPECT
system: AdaptiSPECT-C. In this work, we introduced a new design prototype with multiple …

Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium–zinc–telluride-based SPECT/CT system: a phantom …

R Zhang, M Wang, Y Zhou, S Wang, Y Shen, N Li… - EJNMMI physics, 2021 - Springer
Background The digital cadmium–zinc–telluride (CZT)-based SPECT system has many
advantages, including better spatial and energy resolution. However, the impacts of different …

Multi-pinhole collimator design in different numbers of projections for brain SPECT

W Huang, GSP Mok - Frontiers in Medicine, 2023 - frontiersin.org
Purpose High resolution and sensitivity brain SPECT is promising for the accurate diagnosis
of Alzheimer's disease (AD) and Parkinson's disease (PD). Multi-pinhole (MPH) collimators …

Cerebral SPECT imaging with different acquisition schemes using varying levels of multiplexing versus sensitivity in an adaptive multi-pinhole brain-dedicated …

N Zeraatkar, KS Kalluri, B Auer, M May… - Biomedical physics …, 2021 - iopscience.iop.org
Application of multi-pinhole collimator in pinhole-based SPECT increases detection
sensitivity. The presence of multiplexing in projection images due to the usage of multiple …

Design and development of the DE-SPECT system: a clinical SPECT system for broadband multi-isotope imaging of peripheral vascular disease

EM Zannoni, S Poopalasingam, Y Jin… - Physics in Medicine …, 2024 - iopscience.iop.org
Abstract Objective Peripheral Vascular Disease (PVD) affects more than 230 million people
worldwide and is one of the leading causes of disability among people over age 60 …

Improved performance of a multipinhole SPECT for DAT imaging by increasing number of pinholes at the expense of increased multiplexing

A Könik, N Zeraatkar, KS Kalluri, B Auer… - IEEE transactions on …, 2020 - ieeexplore.ieee.org
Single photon emission tomography imaging of dopamine transporters (DATs) in the brain is
a widely utilized study to improve the diagnosis of Parkinsonian syndromes, where …

Demultiplexing of projection data in adaptive brain SPECT with multi-pinhole collimation

N Zeraatkar, KS Kalluri, B Auer… - 2020 IEEE Nuclear …, 2020 - ieeexplore.ieee.org
Multiplexing of projection images is a potential solution to increasing detection sensitivity in
multi-pinhole (MPH) SPECT systems. However, the ambiguity caused by overlapped …