Progesterone has a broad spectrum of actions in the brain. Among these, the
neuroprotective effects are well documented. Progesterone neural effects are mediated by …

Epidemiologic studies have shown that in the aging society, a person dies from stroke every
3 minutes and 42 seconds, and vast numbers of people experience depression around the …

Background Ischemic stroke can induce changes in mitochondrial morphology and function.
As a regulatory gene in mitochondria, optic atrophy 1 (OPA1) plays a pivotal role in the …

Oxidative stress and deficient bioenergetics are key players in the pathological process of
cerebral ischemia reperfusion injury (I/R). As a mitochondrial iron storage protein …

Recent work has indicated that photobiomodulation (PBM) may beneficially alter the
pathological status of several neurological disorders, although the mechanism currently …

Although progesterone is a steroid hormone mainly associated with female reproductive
functions, such as uterine receptivity and maintenance of pregnancy, accumulating data …

Mammalian mitochondrial permeability transition pore (MPTP), across the inner and outer
membranes of mitochondria, is a nonspecific channel for signal transduction or material …

The mitochondria have a fundamental role in both cellular energy supply and oxidative
stress regulation and are target of the effects of sex steroids, particularly the neuroprotective …

Mitochondrial dysfunction is one of the fundamental causes of ischemia reperfusion (I/R)
damage. I/R refers to the paradoxical progression of cellular dysfunction and death that …

Recent work suggests that repetitive transcranial magnetic stimulation (rTMS) may
beneficially alter the pathological status of several neurological disorders, although the …