Mesoscale physical principles of collective cell organization

X Trepat, E Sahai - Nature Physics, 2018 - nature.com
We review recent evidence showing that cell and tissue dynamics are governed by
mesoscale physical principles. These principles can be understood in terms of simple state …

[HTML][HTML] Ciliogenesis membrane dynamics and organization

H Zhao, Z Khan, CJ Westlake - Seminars in cell & developmental biology, 2023 - Elsevier
Ciliogenesis is a complex multistep process used to describe assembly of cilia and flagella.
These organelles play essential roles in motility and signaling on the surface of cells. Cilia …

Role of internalin proteins in the pathogenesis of Listeria monocytogenes

K Ireton, R Mortuza, GC Gyanwali… - Molecular …, 2021 - Wiley Online Library
Listeria monocytogenes is a food‐borne bacterium that causes gastroenteritis, meningitis, or
abortion. L. monocytogenes induces its internalization (entry) into human cells and either …

BAR domain proteins—a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton

PJ Carman, R Dominguez - Biophysical reviews, 2018 - Springer
Actin filament assembly typically occurs in association with cellular membranes. A large
number of proteins sit at the interface between actin networks and membranes, playing …

Plasma membrane topography governs the 3D dynamic localization of IgM B cell antigen receptor clusters

D Saltukoglu, B Özdemir, M Holtmannspötter… - The EMBO …, 2023 - embopress.org
B lymphocytes recognize bacterial or viral antigens via different classes of the B cell antigen
receptor (BCR). Protrusive structures termed microvilli cover lymphocyte surfaces, and are …

pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism

LM Landau, N Chaudhary, YC Tien, M Rogozinska… - Molecular Cell, 2024 - cell.com
Signal transduction proteins containing a pLxIS motif induce interferon (IFN) responses
central to antiviral immunity. Apart from their established roles in activating the IFN regulator …

Dendritic spine initiation in brain development, learning and diseases and impact of BAR-domain proteins

P Khanal, P Hotulainen - Cells, 2021 - mdpi.com
Dendritic spines are small, bulbous protrusions along neuronal dendrites where most of the
excitatory synapses are located. Dendritic spine density in normal human brain increases …

The evolution of organellar coat complexes and organization of the eukaryotic cell

MP Rout, MC Field - Annual review of biochemistry, 2017 - annualreviews.org
Eukaryotic cells possess a remarkably diverse range of organelles that provide
compartmentalization for distinct cellular functions and are likely responsible for the …

Recent developments in membrane curvature sensing and induction by proteins

C Has, SL Das - Biochimica et Biophysica Acta (BBA)-General Subjects, 2021 - Elsevier
Background Membrane-bound intracellular organelles have characteristic shapes attributed
to different local membrane curvatures, and these attributes are conserved across species …

Insights into membrane curvature sensing and membrane remodeling by intrinsically disordered proteins and protein regions

C Has, P Sivadas, SL Das - The Journal of Membrane Biology, 2022 - Springer
Cellular membranes are highly dynamic in shape. They can rapidly and precisely regulate
their shape to perform various cellular functions. The protein's ability to sense membrane …