[HTML][HTML] Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential

SA Rajput, X Wang, HC Yan - Biomedicine & pharmacotherapy, 2021 - Elsevier
Flavonoids are natural plant-derived dietary bioactive compounds having a substantial
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …

[HTML][HTML] Morin: a Comprehensive Review on its versatile Biological Activity and Associated Therapeutic potential in treating cancers

VKR Balaga, A Pradhan, R Thapa, N Patel… - Pharmacological …, 2023 - Elsevier
Introduction Herbal traditional medicines are used for the treatment of human diseases and
associated complications from the medieval periods. Flavonoids are naturally occurring …

Normalization of HPA axis, cholinergic neurotransmission, and inhibiting brain oxidative and inflammatory dynamics are associated with the adaptogenic-like effect of …

JOT Emudainohwo, B Ben-Azu, OG Adebayo… - Journal of Molecular …, 2023 - Springer
Social defeat stress (SDS) due to changes in biochemical functions has been implicated in
the pathogenesis of affective and cognitive disorders. Employing pharmacological approach …

[HTML][HTML] Impact of sleep disturbances on neurodegeneration: Insight from studies in animal models

JE Owen, SC Veasey - Neurobiology of disease, 2020 - Elsevier
Chronic short sleep or extended wake periods are commonly observed in most
industrialized countries. Previously neurobehavioral impairment following sleep loss was …

Morin decreases cortical pyramidal neuron degeneration via inhibition of neuroinflammation in mouse model of schizophrenia

B Ben-Azu, AO Aderibigbe, AM Ajayi, AEO Eneni… - International …, 2019 - Elsevier
Neuroinflammation plays a prominent role in the pathophysiology and progression of
schizophrenia. Thus, suppression of neuroinflammation may retard the progression of the …

[HTML][HTML] Sleep deficiency promotes Alzheimer's disease development and progression

YN Lv, Y Cui, B Zhang, SM Huang - Frontiers in neurology, 2022 - frontiersin.org
Sleep disorders are a common health problem in modern society. Long-term sleep
deficiency increases the risk for Alzheimer's disease. However, the exact mechanisms by …

Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement

IO Ishola, IO Awogbindin, TG Olubodun-Obadun… - Brain Research, 2022 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
both motor and non-motor functions. It is well reported that the neuropathological process …

[HTML][HTML] Probable mechanisms involved in the antipsychotic-like activity of morin in mice

B Ben-Azu, AO Aderibigbe, IA Omogbiya… - Biomedicine & …, 2018 - Elsevier
Evidence derived from preliminary studies suggests that morin, a neuroactive flavonoid with
proven antioxidant and antiinflammatory properties possess antipsychotic-like activity. The …

The effects of glucagon-like peptide 1 receptor agonist (exenatide) on memory impairment, and anxiety-and depression-like behavior induced by REM sleep …

I Turan, HS Ozacmak, VH Ozacmak, M Ergenc… - Brain Research …, 2021 - Elsevier
Previous investigations have shown that REM sleep deprivation impairs the hippocampus‐
dependent memory, long-term potentiation and causing mood changes. The aim of the …

Involvement of GABAergic, BDNF and Nox-2 mechanisms in the prevention and reversal of ketamine-induced schizophrenia-like behavior by morin in mice

B Ben-Azu, AO Aderibigbe, AM Ajayi, AEO Eneni… - Brain Research …, 2018 - Elsevier
GABAergic (Gamma-aminobutyric acid) and neurotrophic derangements have important
implication in schizophrenia, a neuropsychiatric disease. Previous studies have shown that …