Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

MA Mengstie, E Chekol Abebe… - Frontiers in molecular …, 2022 - frontiersin.org
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to
long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels. By …

AGEs, RAGEs and s-RAGE; friend or foe for cancer

S Ahmad, H Khan, Z Siddiqui, MY Khan… - Seminars in cancer …, 2018 - Elsevier
Impaired awareness of glycation biology in cancer initiation and progression is one of the
fundamental reasons for its meticulous investigation of the molecules involved in signalling …

A new animal diet based on human Western diet is a robust diet-induced obesity model: comparison to high-fat and cafeteria diets in term of metabolic and gut …

RC Bortolin, AR Vargas, J Gasparotto… - International Journal of …, 2018 - nature.com
Methods: Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18
weeks. Metabolic parameters and gut microbiota changes were then characterized. Results …

Protein carbonylation: molecular mechanisms, biological implications, and analytical approaches

M Akagawa - Free Radical Research, 2021 - Taylor & Francis
Proteins are oxidatively modified by a large number of reactive species including reactive
oxygen species, lipid peroxidation-derived aldehydes, and reducing sugars. Among …

Advanced glycation end products dietary restriction effects on bacterial gut microbiota in peritoneal dialysis patients; a randomized open label controlled trial

R Yacoub, M Nugent, W Cai, GN Nadkarni, LD Chaves… - PloS one, 2017 - journals.plos.org
The modern Western diet is rich in advanced glycation end products (AGEs). We have
previously shown an association between dietary AGEs and markers of inflammation and …

Recent advances in detection of AGE s: Immunochemical, bioanalytical and biochemical approaches

JM Ashraf, S Ahmad, I Choi, N Ahmad, M Farhan… - IUBMB …, 2015 - Wiley Online Library
Advanced glycation end products (AGEs) are a cohort of heterogeneous compounds that
are formed after the nonenzymatic glycation of proteins, lipids and nucleic acids …

Plasma protein N-glycan signatures of type 2 diabetes

V Dotz, RFH Lemmers, KR Reiding… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Background Little is known about enzymatic N-glycosylation in type 2 diabetes, a common
posttranslational modification of proteins influencing their function and integrating genetic …

A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models

IMWA Putra, N Fakhrudin, A Nurrochmad, S Wahyuono - Life, 2023 - mdpi.com
Diabetic nephropathy (DN), also recognized as diabetic kidney disease, is a kidney
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …

The emerging role of vitamin B6 in inflammation and carcinogenesis

RP Bird - Advances in food and nutrition research, 2018 - Elsevier
Vitamin B6 serves as a coenzyme catalyzing more than 150 enzymes regulating metabolism
and synthesis of proteins, carbohydrates, lipids, heme, and important bioactive metabolites …

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

MJ Nokin, F Durieux, J Bellier, O Peulen, K Uchida… - Scientific Reports, 2017 - nature.com
Metabolic reprogramming toward aerobic glycolysis unavoidably favours methylglyoxal
(MG) and advanced glycation end products (AGEs) formation in cancer cells. MG was …