Targeting drugs to tumours using cell membrane-coated nanoparticles
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …
specific nature, causing harm to non-malignant tissues. Over the past several decades …
Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive
nanomedical tools because of their unique properties such as immune escape, long blood …
nanomedical tools because of their unique properties such as immune escape, long blood …
Cancer cell-mitochondria hybrid membrane coated Gboxin loaded nanomedicines for glioblastoma treatment
Y Zou, Y Sun, Y Wang, D Zhang, H Yang… - Nature …, 2023 - nature.com
Glioblastoma (GBM) remains the most lethal malignant tumours. Gboxin, an oxidative
phosphorylation inhibitor, specifically restrains GBM growth by inhibiting the activity of F0F1 …
phosphorylation inhibitor, specifically restrains GBM growth by inhibiting the activity of F0F1 …
Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment
Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
A modular approach to enhancing cell membrane-coated nanoparticle functionality using genetic engineering
Since their initial development, cell membrane-coated nanoparticles (CNPs) have become
increasingly popular in the biomedical field. Despite their inherent versatility and ability to …
increasingly popular in the biomedical field. Despite their inherent versatility and ability to …
(Nano) platforms in breast cancer therapy: drug/gene delivery, advanced nanocarriers and immunotherapy
M Ashrafizadeh, A Zarrabi, A Bigham… - Medicinal Research …, 2023 - Wiley Online Library
Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …
Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment
Y Wu, S Wan, S Yang, H Hu, C Zhang, J Lai… - Journal of …, 2022 - Springer
Synthetic nanoparticles with surface bioconjugation are promising platforms for targeted
therapy, but their simple biological functionalization is still a challenging task against the …
therapy, but their simple biological functionalization is still a challenging task against the …
Boosting checkpoint immunotherapy with biomaterials
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
A polymer multicellular nanoengager for synergistic NIR‐II photothermal immunotherapy
Cell‐membrane‐coated nanoparticles (CCNPs) that integrate the biophysiological
advantages of cell membranes with the multifunctionalities of synthetic materials hold great …
advantages of cell membranes with the multifunctionalities of synthetic materials hold great …