Aging is the greatest risk factor for a multitude of diseases including cardiovascular disease,
neurodegeneration and cancer. Despite decades of research dedicated to understanding …

Diabetes has emerged as an epidemic of the 21st century, and retinopathy remains the
leading cause of blindness in young adults and the mechanism of this blinding disease …

Knee osteoarthritis (KOA) is one of the most common degenerative diseases, and its core
feature is the degeneration and damage of articular cartilage. The cartilage degeneration of …

Diabetic retinopathy remains the major cause of blindness among working age adults.
Although a number of metabolic abnormalities have been associated with its development …

Aging is an inherently complex process that is manifested within an organism at genetic,
molecular, cellular, organ, and system levels. Although the fundamental mechanisms are …

Oxygen metabolism is essential for sustaining aerobic life, and normal cellular homeostasis
works on a fine balance between the formation and elimination of reactive oxygen species …

Polyphenols are natural antioxidants and play a very vital role in inhibition of oxidative stress
as induced by free radicals in the body. Apple and pomegranate peels are significant agro …

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycaemia,
with absolute insulin deficiency or insulin resistance as the main cause, and causes damage …

Diabetic retinopathy, a severe sight-threatening complication of diabetes mellitus, accounts
for a large number of cases of acquired, yet potentially avoidable, blindness. The principal …

Oxidative stress (OS) is the imbalance between oxidant and antioxidant molecules, in favor
of oxidants, that causes aging and disease. Many studies have been published that …