Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement …

F Brioude, JM Kalish, A Mussa, AC Foster… - Nat Rev …, 2018 - openaccess.sgul.ac.uk
Beckwith-Wiedemann syndrome (BWS), a human genomic imprinting disorder, is
characterized by phenotypic variability that might include overgrowth, macroglossia …

Hepatoblastoma and pediatric hepatocellular carcinoma: an update

S Ranganathan, D Lopez-Terrada… - Pediatric and …, 2020 - journals.sagepub.com
Hepatoblastomas (HBs) and pediatric hepatocellular carcinomas (HCCs) together account
for almost 80% of primary malignant liver tumors in children and adolescents/young adults …

Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration

RL Meyers, R Maibach, E Hiyama, B Häberle… - The Lancet …, 2017 - thelancet.com
Background Comparative assessment of treatment results in paediatric hepatoblastoma
trials has been hampered by small patient numbers and the use of multiple disparate …

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

J Fang, S Singh, C Cheng, S Natarajan… - Nature …, 2023 - nature.com
A lack of relevant genetic models and cell lines hampers our understanding of
hepatoblastoma pathogenesis and the development of new therapies for this neoplasm …

Hepatoblastoma state of the art: pathology, genetics, risk stratification, and chemotherapy

P Czauderna, D Lopez-Terrada, E Hiyama… - Current opinion in …, 2014 - journals.lww.com
International collaborative efforts in hepatoblastoma have led to a new international
histopathologic consensus classification, refinements in risk stratification, advances in …

Surveillance recommendations for children with overgrowth syndromes and predisposition to Wilms tumors and hepatoblastoma

JM Kalish, L Doros, LJ Helman, RC Hennekam… - Clinical Cancer …, 2017 - AACR
A number of genetic syndromes have been linked to increased risk for Wilms tumor (WT),
hepatoblastoma (HB), and other embryonal tumors. Here, we outline these rare syndromes …

[PDF][PDF] Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups

P Sumazin, Y Chen, LR Treviño, SF Sarabia… - …, 2017 - Wiley Online Library
Despite being the most common liver cancer in children, hepatoblastoma (HB) is a rare
neoplasm. Consequently, few pretreatment tumors have been molecularly profiled, and …

Pyrrolizidine alkaloids: potential role in the etiology of cancers, pulmonary hypertension, congenital anomalies, and liver disease

JA Edgar, RJ Molyneux… - Chemical research in …, 2015 - ACS Publications
Large outbreaks of acute food-related poisoning, characterized by hepatic sinusoidal
obstruction syndrome, hemorrhagic necrosis, and rapid liver failure, occur on a regular basis …

Association between birth defects and cancer risk among children and adolescents in a population-based assessment of 10 million live births

PJ Lupo, JM Schraw, TA Desrosiers… - JAMA …, 2019 - jamanetwork.com
Importance Birth defects affect approximately 1 in 33 children. Some birth defects are known
to be strongly associated with childhood cancer (eg, trisomy 21 and acute leukemia) …

Curcumin and liver disease

L Vera‐Ramirez, P Pérez‐Lopez, A Varela‐Lopez… - Biofactors, 2013 - Wiley Online Library
Liver diseases pose a major medical problem worldwide and a wide variety of herbs have
been studied for the management of liver‐related diseases. In this respect, curcumin has …