The functions of CAP superfamily proteins in mammalian fertility and disease

AS Gaikwad, J Hu, DG Chapple… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Members of the cysteine-rich secretory proteins (CRISPS), antigen 5 (Ag5)
and pathogenesis-related 1 (Pr-1)(CAP) superfamily of proteins are found across the …

MSMB variation and prostate cancer risk: Clues towards a possible fungal etiology

S Sutcliffe, AM De Marzo, KS Sfanos… - The Prostate, 2014 - Wiley Online Library
ABSTRACT BACKGROUND. With recent advances in high‐throughput sequencing
technologies, many prostate cancer risk loci have been identified, including rs10993994, a …

CRISP3 expression drives prostate cancer invasion and progression

M Volpert, L Furic, J Hu, AE O'Connor… - Endocrine-Related …, 2020 - erc.bioscientifica.com
Identifying the factors stimulating prostate cancer cells migration and invasion has the
potential to bring new therapeutic targets to the clinic. Cysteine-rich secretory protein 3 …

[HTML][HTML] Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical …

K Grupp, S Kohl, H Sirma, R Simon, S Steurer… - Modern Pathology, 2013 - Elsevier
The aim of this study was to determine whether cysteine-rich secretory protein 3 (CRISP3)
expression is linked to clinically or molecularly relevant subgroups of prostate cancer. A …

Site-specific and common prostate cancer metastasis genes as suggested by meta-analysis of gene expression data

I Samaržija - Life, 2021 - mdpi.com
Anticancer therapies mainly target primary tumor growth and little attention is given to the
events driving metastasis formation. Metastatic prostate cancer, in comparison to localized …

Prostate secretory protein 94 inhibits sterol binding and export by the mammalian CAP protein CRISP2 in a calcium-sensitive manner

O El Atab, AE Kocabey, OA Asojo… - Journal of Biological …, 2022 - ASBMB
Members of the CAP protein superfamily are present in all kingdoms of life and have been
implicated in many different processes, including pathogen defense, immune evasion …

Cysteine-rich secretory protein 3 plays a role in prostate cancer cell invasion and affects expression of PSA and ANXA1

BR Pathak, AA Breed, S Apte, K Acharya… - Molecular and cellular …, 2016 - Springer
Cysteine-rich secretory protein 3 (CRISP-3) is upregulated in prostate cancer as compared
to the normal prostate tissue. Higher expression of CRISP-3 has been linked to poor …

Screening differentially expressed proteins of coronary heart disease with congenital cold syndrome based on tandem mass tag (TMT) technology

T Xie, J Guo, Y Jiang, L Li, L Jiang, Y Wei - Bioengineered, 2021 - Taylor & Francis
In our previous studies, we discovered the congenital cold syndrome (CCS), which is
characterized by 'qi deficiency and qi stagnation, mixed cold and heat.'And there is a type of …

SRC kinase regulation in progressively invasive cancer

W Xu, N Allbritton, DS Lawrence - PLoS One, 2012 - journals.plos.org
Metastatic progression is a multistep process that involves tumor growth and survival,
motility and invasion, and subsequent proliferation in an inappropriate environment. The Src …

The rs10993994 in the proximal MSMB promoter region is a functional polymorphism in Asian Indian subjects

DR Mhatre, SD Mahale, MI Khatkhatay, SK Achrekar… - Springerplus, 2015 - Springer
Background The microseminoprotein gene encoding prostate secretory protein of 94 amino
acids (PSP94) harbours a potential risk allele (rs10993994) for prostate cancer (PCa) in its …