Therapeutic potential of tumor metabolic reprogramming in triple-negative breast cancer
G Munkácsy, L Santarpia, B Győrffy - International Journal of Molecular …, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with
clinical features of high metastatic potential, susceptibility to relapse, and poor prognosis …
clinical features of high metastatic potential, susceptibility to relapse, and poor prognosis …
Investigating the role of natural flavonoids in VEGFR inhibition: Molecular modelling and biological activity in A549 lung cancer cells
Genetics, lifestyle, and hormones influence lung cancer, the most common malignancy in
the world. VEGFR plays a key role in tumor growth and metastasis by promoting …
the world. VEGFR plays a key role in tumor growth and metastasis by promoting …
Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancer
JD Li, AA Farah, ZG Huang, GQ Zhai, RG Wang, JL Liu… - BMC cancer, 2022 - Springer
Background Pituitary tumor transforming gene-1 (PTTG1) transcription factor is identified as
carcinogenic and associated with tumor invasiveness, but its role in bladder cancer (BLCA) …
carcinogenic and associated with tumor invasiveness, but its role in bladder cancer (BLCA) …
Syntheses, crystal structure, luminescent properties and Hirshfeld surface of a set of triazole-based salts
BQ Jin, YQ Song, YX Ma, Y Zhou, GM Tang… - Journal of Molecular …, 2023 - Elsevier
To further investigate and explore the new luminescent materials, three new salts with
triazole-based skeletons, namely,[HCNT]+ X−(X= BS (1), PS (2) and SS∙ H 2 O (3))[CNT= 4 …
triazole-based skeletons, namely,[HCNT]+ X−(X= BS (1), PS (2) and SS∙ H 2 O (3))[CNT= 4 …
Pioneering simultaneous determination of breast cancer medications and metformin through sustainable micellar electrokinetic chromatographic method
The current study is the first report for the capillary electrophoretic simultaneous
determination of five breast cancer medications, including febuxostat, quercetin, letrozole …
determination of five breast cancer medications, including febuxostat, quercetin, letrozole …
Design, synthesis, computational studies and evaluation of novel 2, 4, 5-trisubstituted pyrimidine derivatives for anticancer activity against MCF-7 and A549 cell lines
Synthesized novel trisubstituted pyrimidine derivatives (U 01–15) were tested for anti-cancer
efficacy against two cancer cell line MCF-7 and A549. Several spectroscopic methods …
efficacy against two cancer cell line MCF-7 and A549. Several spectroscopic methods …
Aromatase inhibitors identified from Saraca asoca to treat infertility in women with polycystic ovary syndrome via in silico and in vivo studies
K Himaja, K Veerapandiyan, B Usha - Journal of Biomolecular …, 2024 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a widely occurring metabolic disorder causing
infertility in 70%–80% of the affected women. Saraca asoca, an ancient medicinal herb, has …
infertility in 70%–80% of the affected women. Saraca asoca, an ancient medicinal herb, has …
Computational Exploration of Naturally Occurring Flavonoids as TGF‐β Inhibitors in Breast Cancer: Insights from Docking and Molecular Dynamics Simulations and In …
Breast cancer is a global health concern, demanding innovative treatments. Targeting the
Transforming Growth Factor‐beta (TGF‐β) signaling pathway, pivotal in breast cancer, is a …
Transforming Growth Factor‐beta (TGF‐β) signaling pathway, pivotal in breast cancer, is a …
Repurposing Phytochemicals against Breast Cancer (MCF-7) using Classical Structure-Based Drug Design
FEH Aldoghachi, A Oraibi, NH Mohsen… - Current Drug …, 2025 - benthamdirect.com
Background The significant public health effect of breast cancer is demonstrated by its high
global prevalence and the potential for severe health consequences. The suppression of the …
global prevalence and the potential for severe health consequences. The suppression of the …
Investigating the Antioxidant Capacity of Newly Synthesized Flavonoids via DPPH Assay
Background: Numerous naturally occurring and artificially synthesized flavonoids have
garnered attention for their impressive ability to combat oxidative stress and scavenge free …
garnered attention for their impressive ability to combat oxidative stress and scavenge free …