Machine learning for brain age prediction: Introduction to methods and clinical applications

L Baecker, R Garcia-Dias, S Vieira, C Scarpazza… - …, 2021 - thelancet.com
The rise of machine learning has unlocked new ways of analysing structural neuroimaging
data, including brain age prediction. In this state-of-the-art review, we provide an …

Accelerating research on biological aging and mental health: Current challenges and future directions

LKM Han, JE Verhoeven, AR Tyrka… - …, 2019 - Elsevier
Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

A nonlinear simulation framework supports adjusting for age when analyzing BrainAGE

TT Le, RT Kuplicki, BA McKinney, HW Yeh… - Frontiers in aging …, 2018 - frontiersin.org
Several imaging modalities, including T1-weighted structural imaging, diffusion tensor
imaging, and functional MRI can show chronological age related changes. Employing …

Brain-age prediction: A systematic comparison of machine learning workflows

S More, G Antonopoulos, F Hoffstaedter, J Caspers… - NeuroImage, 2023 - Elsevier
The difference between age predicted using anatomical brain scans and chronological age,
ie, the brain-age delta, provides a proxy for atypical aging. Various data representations and …

Detect and correct bias in multi-site neuroimaging datasets

C Wachinger, A Rieckmann, S Pölsterl… - Medical Image …, 2021 - Elsevier
The desire to train complex machine learning algorithms and to increase the statistical
power in association studies drives neuroimaging research to use ever-larger datasets. The …

Brain age prediction: A comparison between machine learning models using region‐and voxel‐based morphometric data

L Baecker, J Dafflon, PF Da Costa… - Human brain …, 2021 - Wiley Online Library
Brain morphology varies across the ageing trajectory and the prediction of a person's age
using brain features can aid the detection of abnormalities in the ageing process. Existing …

Brain-predicted age difference score is related to specific cognitive functions: a multi-site replication analysis

R Boyle, L Jollans, LM Rueda-Delgado, R Rizzo… - Brain imaging and …, 2021 - Springer
Brain-predicted age difference scores are calculated by subtracting chronological age from
'brain'age, which is estimated using neuroimaging data. Positive scores reflect accelerated …

Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging

X Feng, ZC Lipton, J Yang, SA Small… - Neurobiology of …, 2020 - Elsevier
Numerous studies have established that estimated brain age constitutes a valuable
biomarker that is predictive of cognitive decline and various neurological diseases. In this …

[HTML][HTML] Fetal brain age estimation and anomaly detection using attention-based deep ensembles with uncertainty

W Shi, G Yan, Y Li, H Li, T Liu, C Sun, G Wang… - Neuroimage, 2020 - Elsevier
MRI-based brain age prediction has been widely used to characterize normal brain
development, and deviations from the typical developmental trajectory are indications of …

Deep relation learning for regression and its application to brain age estimation

S He, Y Feng, PE Grant, Y Ou - IEEE transactions on medical …, 2022 - ieeexplore.ieee.org
Most deep learning models for temporal regression directly output the estimation based on
single input images, ignoring the relationships between different images. In this paper, we …