Liver cancer or hepatocellular carcinoma (HCC) is leading cause of cancer-related
mortalities globally. The therapeutic approaches for chronic liver diseases-associated liver …

Hepatic fibrosis and cirrhosis cause strong human suffering and necessitate a monetary
burden worldwide. Therefore, there is an urgent need for the development of therapies. Pre …

Activation of quiescent hepatic stellate cells (HSCs) is the major event in hepatic
fibrogenesis, along with enhancement of cell proliferation and overproduction of …

Background & Aims miR‐122 is the most abundant mi RNA in the liver particularly in
hepatocytes where it targets cholesterol metabolism. Steatosis, a key component of non …

Background Human amniotic membrane-derived mesenchymal stem cells (hAMCs) have
the potential to reduce heart and lung fibrosis, but whether could reduce liver fibrosis …

Most chronic liver diseases progress to liver fibrosis, which, when left untreated, can lead to
cirrhosis and hepatocellular carcinoma. MicroRNA (miRNA)-targeted therapeutics have …

Ascorbate (vitamin C in primates) functions as a cofactor for a number of enzymatic reactions
represented by prolyl hydroxylases and as an antioxidant due to its ability to donate …

We previously reported the promising effects of dioscin against liver injury, but its effect on
liver fibrosis remains unknown. The present work investigated the activities of dioscin …

Liver fibrosis is a common link in the transformation of acute and chronic liver diseases to
cirrhosis. It is of great clinical significance to study the factors associated with the induction of …

Adequate nutrition is vital for immune homeostasis. However, the incidence of obesity is
increasing worldwide due to the adoption of the Western diet and a sedentary lifestyle …