The inter-relationship between delirium and dementia: the importance of delirium prevention
Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …
and have a distinct, complex and interconnected relationship. Delirium is an acute …
Neurofilament proteins as biomarkers to monitor neurological diseases and the efficacy of therapies
Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
Comparison of serum neurodegenerative biomarkers among hospitalized COVID‐19 patients versus non‐COVID subjects with normal cognition, mild cognitive …
JA Frontera, A Boutajangout, AV Masurkar… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Neurological complications among hospitalized COVID‐19 patients may be
associated with elevated neurodegenerative biomarkers. Methods Among hospitalized …
associated with elevated neurodegenerative biomarkers. Methods Among hospitalized …
The multifaceted role of neurofilament light chain protein in non-primary neurological diseases
The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
Six-year cognitive trajectory in older adults following major surgery and delirium
Importance The study results suggest that delirium is the most common postoperative
complication in older adults and is associated with poor outcomes, including long-term …
complication in older adults and is associated with poor outcomes, including long-term …
Delirium, neurofilament light chain, and progressive cognitive impairment: analysis of a prospective Norwegian population-based cohort
M Krogseth, D Davis, TA Jackson… - The Lancet Healthy …, 2023 - thelancet.com
Background Previous population-based, longitudinal studies have shown that delirium is
associated with an increased risk of dementia and cognitive decline. However, the …
associated with an increased risk of dementia and cognitive decline. However, the …
Preoperative plasma Tau-PT217 and Tau-PT181 are associated with postoperative delirium
Objective: This study aims to identify blood biomarkers of postoperative delirium.
Background: Phosphorylated tau at threonine 217 (Tau-PT217) and 181 (Tau-PT181) are …
Background: Phosphorylated tau at threonine 217 (Tau-PT217) and 181 (Tau-PT181) are …
The 2022 lady estelle wolfson lectureship on neurofilaments
A Petzold - Journal of neurochemistry, 2022 - Wiley Online Library
Neurofilament proteins (Nf) have been validated and established as a reliable body fluid
biomarker for neurodegenerative pathology. This review covers seven Nf isoforms, Nf light …
biomarker for neurodegenerative pathology. This review covers seven Nf isoforms, Nf light …
Biomarkers of delirium risk in older adults: a systematic review and meta-analysis
L Lozano-Vicario, A García-Hermoso… - Frontiers in Aging …, 2023 - frontiersin.org
Delirium is a neuropsychiatric syndrome associated with increased morbidity and mortality
in older patients. The aim of this study was to review predictive biomarkers of delirium in …
in older patients. The aim of this study was to review predictive biomarkers of delirium in …
Mitigation of perioperative neurocognitive disorders: A holistic approach
William Morton introduced the world to ether anesthesia for use during surgery in the
Bullfinch Building of the Massachusetts General Hospital on October 16, 1846. For nearly …
Bullfinch Building of the Massachusetts General Hospital on October 16, 1846. For nearly …