Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

Based on the availability of many nutrients, Moringa oleifera tree leaves have been widely
employed as nutrients and nutraceuticals in recent years. The leaves contain a small …

Nutritional excess is a major forerunner of type 2 diabetes. It enhances the secretion of
insulin, but attenuates insulin's metabolic actions in the liver, skeletal muscle and adipose …

The worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to have
reached 25% or more in adults. NAFLD is prevalent in obese individuals, but may also affect …

Polycystic ovary syndrome (PCOS) affects 5–20% of women of reproductive age worldwide.
The condition is characterized by hyperandrogenism, ovulatory dysfunction and polycystic …

In this paper, the biosynthesis process of phenolic compounds in plants is summarized,
which include the shikimate, pentose phosphate and phenylpropanoid pathways. Plant …

The genus Cinnamomum includes a number of plant species largely used as food, food
additives and spices for a long time. Different traditional healing systems have used these …

Lipotoxicity, originally used to describe the destructive effects of excess fat accumulation on
glucose metabolism, causes functional impairments in several metabolic pathways, both in …

Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis,
resulting in hyperglycaemia. Although current diabetes treatments have exhibited some …

Metabolic dysfunction is a well-established feature of Alzheimer's disease (AD), evidenced
by brain glucose hypometabolism that can be observed potentially decades prior to the …