Metabolic host responses to infection by intracellular bacterial pathogens
W Eisenreich, J Heesemann, T Rudel… - Frontiers in cellular and …, 2013 - frontiersin.org
The interaction of bacterial pathogens with mammalian hosts leads to a variety of
physiological responses of the interacting partners aimed at an adaptation to the new …
physiological responses of the interacting partners aimed at an adaptation to the new …
Mass spectrometry-based proteomic approaches to study pathogenic bacteria-host interactions
Y Yang, M Hu, K Yu, X Zeng, X Liu - Protein & cell, 2015 - academic.oup.com
Elucidation of molecular mechanisms underlying host-pathogen interactions is important for
control and treatment of infectious diseases worldwide. Within the last decade, mass …
control and treatment of infectious diseases worldwide. Within the last decade, mass …
Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence
B Steeb, B Claudi, NA Burton, P Tienz, A Schmidt… - PLoS …, 2013 - journals.plos.org
Pathogen access to host nutrients in infected tissues is fundamental for pathogen growth
and virulence, disease progression, and infection control. However, our understanding of …
and virulence, disease progression, and infection control. However, our understanding of …
Model‐driven multi‐omic data analysis elucidates metabolic immunomodulators of macrophage activation
A Bordbar, ML Mo, ES Nakayasu… - Molecular systems …, 2012 - embopress.org
Macrophages are central players in immune response, manifesting divergent phenotypes to
control inflammation and innate immunity through release of cytokines and other signaling …
control inflammation and innate immunity through release of cytokines and other signaling …
[HTML][HTML] Thymol disrupts the membrane integrity of Salmonella ser. typhimurium in vitro and recovers infected macrophages from oxidative stress in an ex vivo model
AK Chauhan, SC Kang - Research in microbiology, 2014 - Elsevier
Salmonella is a common bacterial enteropathogen responsible for many deaths every year.
In the present study, we evaluated the mechanism of action of thymol against Salmonella …
In the present study, we evaluated the mechanism of action of thymol against Salmonella …
Reprogramming of macrophages employing gene regulatory and metabolic network models
F Hörhold, D Eisel, M Oswald, A Kolte… - PLoS computational …, 2020 - journals.plos.org
Upon exposure to different stimuli, resting macrophages undergo classical or alternative
polarization into distinct phenotypes that can cause fatal dysfunction in a large range of …
polarization into distinct phenotypes that can cause fatal dysfunction in a large range of …
Metabolic adaptations of intracellullar bacterial pathogens and their mammalian host cells during infection (“pathometabolism”)
W Eisenreich, J Heesemann, T Rudel… - Metabolism and …, 2015 - Wiley Online Library
Metabolic adaptation reactions are common when prokaryotes interact with eukaryotic cells,
especially when the bacteria are internalized by these host cells. Such adaptations lead to …
especially when the bacteria are internalized by these host cells. Such adaptations lead to …
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection
The interplay between host and pathogen relies heavily on rapid protein synthesis and
accurate protein targeting to ensure pathogen destruction. To gain insight into this dynamic …
accurate protein targeting to ensure pathogen destruction. To gain insight into this dynamic …
Foodomics and food safety: Where we are
U Andjelković, M Šrajer Gajdošik… - Food Technology and …, 2017 - hrcak.srce.hr
Sažetak The power of foodomics as a discipline that is now broadly used for quality
assurance of food products and adulteration identification, as well as for determining the …
assurance of food products and adulteration identification, as well as for determining the …
Impact of Salmonella Infection on Host Hormone Metabolism Revealed by Metabolomics
LCM Antunes, ET Arena, A Menendez, J Han… - Infection and …, 2011 - Am Soc Microbiol
The interplay between pathogens and their hosts has been studied for decades using
targeted approaches, such as the analysis of mutants and host immunological responses …
targeted approaches, such as the analysis of mutants and host immunological responses …